Withanage Nishadi Nethmini, Botfield Jessica R, Srinivasan Sonia, Black Kirsten I, Mazza Danielle
Department of General Practice, Monash University, Clayton, Australia
Department of General Practice, Monash University, Clayton, Australia.
BJGP Open. 2022 Aug 30;6(2). doi: 10.3399/BJGPO.2021.0191. Print 2022 Jun.
Pregnancy outcomes can be adversely affected by a range of modifiable risk factors, including alcohol consumption, smoking, obesity, drug use, and poor nutrition, during the preconception period. Preconception care (PCC) involves interventions that identify and seek to change behavioural, biomedical, and social risks present in reproductive-aged women and men. Primary care is well situated to offer PCC interventions but the effectiveness of these interventions is not clear.
To evaluate the effectiveness of primary care-based PCC delivered to reproductive-aged women and/or men to improve health knowledge, reduce preconception risk factors, and improve pregnancy outcomes.
DESIGN & SETTING: A systematic review of primary care-based PCC.
Ovid MEDLINE, Cochrane Central Register of Controlled Trials, Embase, Web of Science, Scopus, and the Cumulative Index to Nursing and Allied Health Literature (CINAHL) databases will be searched for English language studies published between July 1999 and May 2021. For inclusion, the PCC intervention must be provided in a primary care setting and intervention recipients must be reproductive-aged women and/or men. All stages of screening and data extraction will involve a dual review. The Cochrane Risk of Bias 2 (RoB 2) for randomised controlled trials (RCTs) will be used to assess the methodological quality of studies. This protocol adheres to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols (PRISMA-P) reporting guidelines.
Findings will determine the effectiveness of primary care-based preconception interventions delivered to reproductive-aged women and men on improving health knowledge, reducing risk factors, and improving pregnancy outcomes. Findings will be published in a peer-reviewed journal.
孕前期间,一系列可改变的风险因素会对妊娠结局产生不利影响,这些因素包括饮酒、吸烟、肥胖、药物使用和营养不良。孕前保健(PCC)涉及识别并试图改变育龄期女性和男性存在的行为、生物医学和社会风险的干预措施。初级保健机构具备提供孕前保健干预措施的条件,但这些干预措施的有效性尚不清楚。
评估针对育龄期女性和/或男性提供的基于初级保健的孕前保健在提高健康知识、降低孕前风险因素及改善妊娠结局方面的有效性。
对基于初级保健的孕前保健进行系统评价。
将检索Ovid MEDLINE、Cochrane对照试验中心注册库、Embase、科学网、Scopus以及护理与健康照护领域累积索引数据库(CINAHL),查找1999年7月至2021年5月发表的英文研究。纳入标准为,孕前保健干预措施必须在初级保健机构提供,且干预接受者必须是育龄期女性和/或男性。筛查和数据提取的所有阶段都将进行双人审核。随机对照试验(RCT)将采用Cochrane偏倚风险2(RoB 2)来评估研究的方法学质量。本方案遵循系统评价和Meta分析方案的首选报告项目(PRISMA-P)报告指南。
研究结果将确定针对育龄期女性和男性提供的基于初级保健的孕前干预措施在提高健康知识、降低风险因素及改善妊娠结局方面的有效性。研究结果将发表在同行评审期刊上。