Petrov R V, Dozmorov I M, Kochetkova M O, Nikolaeva I S
Biull Eksp Biol Med. 1986 May;101(5):586-7.
The interaction of lymphocytes from mouse lymph nodes with allogeneic stem cells was studied using exogenous colony formation inhibition test. Dual nature of the interaction was revealed: great amounts of lymphocytes inhibited, while small amounts stimulated colony formation. This dependence holds true for macro- and microcolonies as well as for erythrocyte and granuloid microcolonies in the bone marrow during fixation on day 8 and 11 after cell mixture transplantation.
利用外源性集落形成抑制试验研究了小鼠淋巴结淋巴细胞与同种异体干细胞的相互作用。揭示了这种相互作用的双重性质:大量淋巴细胞抑制集落形成,而少量淋巴细胞则刺激集落形成。这种依赖性在细胞混合物移植后第8天和第11天固定时,对于骨髓中的大、微集落以及红细胞和粒细胞微集落同样适用。