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DEMS-DOSS 研究:验证一种用于住院老年患者的谵妄监测工具。

The DEMS-DOSS study: validating a delirium monitoring tool in hospitalised older adults.

机构信息

School of Nursing, Faculty of Science, Medicine and Health, University of Wollongong, New South Wales, 2522, Australia.

Aged Care Department, St. George Hospital, Kogarah, New South Wales 2217, Australia.

出版信息

Age Ageing. 2022 Feb 2;51(2). doi: 10.1093/ageing/afac012.

Abstract

OBJECTIVE

to evaluate the sensitivity, specificity and test-retest reliability of the Delirium Early Monitoring System-Delirium Observation Screening Scale (DEMS-DOSS).

DESIGN

prospective diagnostic accuracy study of a convenience sample of admitted older adults with DEMS-DOSS and reference standard assessments.

SETTING

60-bed aged care precinct at a metropolitan hospital in Sydney, Australia.

PARTICIPANTS

156 patients (aged ≥65 years old) were recruited to participate between April 2018 and March 2020. One hundred participants were included in the analysis.

MEASUREMENTS

Participants were scored on the DEMS-DOSS. Trained senior aged care nurses conducted a standardised clinical interview based on the Diagnostic and Statistical Manual of Mental Disorder (DSM)-IV delirium criteria, within two hours of DEMS-DOSS completion. The senior aged care nurse undertaking the DSM-IV interview was blinded to the results of the DEMS-DOSS.

RESULTS

Participants' mean age was 84 (SD ±7.3) years and 39% (n = 39) had a documented diagnosis of dementia. Delirium was detected in 38% (n = 38) according to the reference standard. The DEMS-DOSS had a sensitivity of 76.3% and a specificity of 75.8% for delirium. The area under the receiver operating characteristics curve for delirium was 0.76. The test-retest reliability of the DEMS-DOSS was found to be high (r = 0.915).

CONCLUSION

DEMS-DOSS is a sensitive and specific tool to assist with monitoring new onset and established delirium in hospitalised older adults. Further studies are required to evaluate the impact of the monitoring tool on health outcomes.

摘要

目的

评估 Delirium Early Monitoring System-Delirium Observation Screening Scale(DEMS-DOSS)的敏感性、特异性和重测信度。

设计

对接受 DEMS-DOSS 和参考标准评估的便利样本的住院老年患者进行前瞻性诊断准确性研究。

地点

澳大利亚悉尼一家都市医院的 60 张床位老年护理区。

参与者

2018 年 4 月至 2020 年 3 月期间,共招募了 156 名(年龄≥65 岁)患者参与研究。100 名参与者被纳入分析。

测量

参与者接受 DEMS-DOSS 评分。经过培训的老年护理护士根据精神障碍诊断与统计手册(DSM-IV)的谵妄标准,在完成 DEMS-DOSS 后两小时内进行标准化临床访谈。进行 DSM-IV 访谈的老年护理护士对 DEMS-DOSS 的结果不知情。

结果

参与者的平均年龄为 84(SD±7.3)岁,39%(n=39)有记录的痴呆症诊断。根据参考标准,38%(n=38)检测到谵妄。DEMS-DOSS 对谵妄的敏感性为 76.3%,特异性为 75.8%。用于诊断谵妄的受试者工作特征曲线下面积为 0.76。DEMS-DOSS 的重测信度被发现很高(r=0.915)。

结论

DEMS-DOSS 是一种用于监测住院老年患者新发和已确诊谵妄的敏感且特异的工具。需要进一步的研究来评估监测工具对健康结果的影响。

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