Institute of Neuromedicine and Movement Science (INB), Norwegian University of Science and Technology (NTNU), Trondheim, Norway.
Department of Otolaryngology, Head and Neck Surgery, Molde Sjukehus, Helse Møre og Romsdal, 6412, Molde, Norway.
Eur Arch Otorhinolaryngol. 2022 Oct;279(10):4925-4933. doi: 10.1007/s00405-022-07298-7. Epub 2022 Feb 23.
The lack of epidemiological data on the proportion of olfactory dysfunction (OD) using comprehensive olfactory assessment in healthy adults in Scandinavia motivated to the present study which aimed to explore the proportion of OD in voluntary healthy Norwegian adults, assessed by Sniffin' Sticks, and its correlation to self-reported olfactory function. Furthermore, sociodemographic and clinical factors associated with olfactory function were analysed.
The sample included 405 Norwegian participants, aged 18-78 years, 273 women and 132 men, who underwent olfactory testing with extensive Sniffin' Sticks test, allergy testing, clinical examination with nasal endoscopy and completed a self-administered questionnaire, including self-evaluation of olfactory function on a 100 mm Visual Analogue Scale.
We found that 37% had OD, of which 1.2% had anosmia assessed with extensive Sniffin' Sticks test. The proportion of hyposmia and anosmia increased with age. Men and participants with low education had poorer olfactory function scores. Allergy, smoking status, general health and endoscopic findings were not associated with measured olfactory function. We found no correlation between self-reported and measured olfactory function.
This study has identified that a large proportion of our sample of voluntary healthy Norwegian adults have OD, considerably more common in older adults and somewhat more common in men and individuals with low education. The lack of correlation between self-reported and measured olfactory function highlights the importance of using validated tests for a reliable olfactory evaluation.
斯堪的纳维亚地区缺乏使用综合性嗅觉评估方法评估健康成年人嗅觉障碍(OD)比例的流行病学数据,这促使本研究旨在探索通过嗅觉测试棒评估的、自愿参加的挪威健康成年人中 OD 的比例及其与自我报告嗅觉功能的相关性。此外,还分析了与嗅觉功能相关的社会人口学和临床因素。
该样本包括 405 名年龄在 18-78 岁的挪威参与者,其中 273 名女性,132 名男性,他们接受了广泛的嗅觉测试棒测试、过敏测试、鼻内窥镜临床检查,并完成了一份自我管理问卷,包括使用 100 毫米视觉模拟量表自我评估嗅觉功能。
我们发现 37%的人存在 OD,其中 1.2%的人存在广泛嗅觉测试棒评估的嗅觉丧失。嗅觉减退和嗅觉丧失的比例随着年龄的增长而增加。男性和受教育程度较低的参与者嗅觉功能评分较差。过敏、吸烟状况、总体健康状况和内窥镜检查结果与测量的嗅觉功能无关。我们没有发现自我报告和测量的嗅觉功能之间存在相关性。
本研究表明,我们的自愿性健康挪威成年人样本中存在大量 OD,老年人更为常见,男性和受教育程度较低的个体更为常见。自我报告和测量的嗅觉功能之间缺乏相关性强调了使用经过验证的测试进行可靠嗅觉评估的重要性。