Yang Liping, Li Chunbo, Li Xiumei, Zhai Manman, An Qingqing, Zhang You, Zhao Jing, Weng Xuchu
Key Laboratory of Brain, Cognition and Education Sciences, Ministry of Education, Guangzhou 510631, China.
School of Psychology, South China Normal University, Guangzhou 510631, China.
Brain Sci. 2022 Feb 10;12(2):240. doi: 10.3390/brainsci12020240.
Developmental dyslexia (DD) is a specific learning disorder concerning reading acquisition that may has a lifelong negative impact on individuals. A reliable estimate of the prevalence of DD serves as the basis for diagnosis, intervention, and evidence-based health resource allocation and policy-making. Hence, the present meta-analysis aims to generate a reliable prevalence estimate of DD worldwide in primary school children and explore the potential variables related to that prevalence.
Studies from the 1950s to June 2021 were collated using a combination of search terms related to DD and prevalence. Study quality was assessed using the STROBE guidelines according to the study design, with study heterogeneity assessed using the statistic, and random-effects meta-analyses were conducted. Variations in the prevalence of DD in different subgroups were assessed via subgroup meta-analysis and meta-regression.
The pooled prevalence of DD was 7.10% (95% CI: 6.27-7.97%). The prevalence in boys was significantly higher than that in girls (boys: 9.22%, 95%CI, 8.07-10.44%; girls: 4.66%, 95% CI, 3.84-5.54%; < 0.001), but no significant difference was found in the prevalence across different writing systems (alphabetic scripts: 7.26%, 95%CI, 5.94-8.71%; logographic scripts: 6.97%, 95%CI, 5.86-8.16%; > 0.05) or across different orthographic depths (shallow: 7.13%, 95% CI, 5.23-9.30%; deep: 7.55%, 95% CI, 4.66-11.04%; > 0.05). It is worth noting that most articles had small sample sizes with diverse operational definitions, making comparisons challenging.
This study provides an estimation of worldwide DD prevalence in primary school children. The prevalence was higher in boys than in girls but was not significantly different across different writing systems.
发育性阅读障碍(DD)是一种与阅读习得有关的特定学习障碍,可能会对个体产生终身负面影响。对DD患病率的可靠估计是诊断、干预以及循证卫生资源分配和政策制定的基础。因此,本荟萃分析旨在得出全球范围内小学生DD的可靠患病率估计值,并探索与该患病率相关的潜在变量。
使用与DD和患病率相关的搜索词组合,整理了20世纪50年代至2021年6月的研究。根据研究设计,使用STROBE指南评估研究质量,使用统计量评估研究异质性,并进行随机效应荟萃分析。通过亚组荟萃分析和荟萃回归评估不同亚组中DD患病率的差异。
DD的合并患病率为7.10%(95%CI:6.27 - 7.97%)。男孩的患病率显著高于女孩(男孩:9.22%,95%CI,8.07 - 10.44%;女孩:4.66%,95%CI,3.84 - 5.54%;<0.001),但不同书写系统(字母文字:7.26%,95%CI,5.94 - 8.71%;表意文字:6.97%,95%CI,5.86 - 8.16%;>0.05)或不同正字法深度(浅:7.13%,95%CI,5.23 - 9.30%;深:7.55%,95%CI,4.66 - 11.04%;>0.05)之间的患病率无显著差异。值得注意的是,大多数文章样本量较小且操作定义多样,使得比较具有挑战性。
本研究提供了全球小学生DD患病率的估计值。男孩的患病率高于女孩,但不同书写系统之间无显著差异。