Department of Chemistry, The Natural Science Research Institute, Myongji University, 116 Myongji ro, Yongin 17058, Gyeonggi-do, Korea.
Int J Mol Sci. 2022 Feb 9;23(4):1943. doi: 10.3390/ijms23041943.
In the era of nanotechnology, the synthesis of nanomaterials for advanced applications has grown enormously. Effective therapeutics and functionalization of effective drugs using nano-vehicles are considered highly productive and selectively necessary. Polymeric nanomaterials have shown their impact and influential role in this process. Polymeric nanomaterials in molecular science are well facilitated due to their low cytotoxic behavior, robust functionalization, and practical approach towards in vitro and in vivo therapeutics. This review highlights a brief discussion on recent techniques used in nanohydrogel designs, biomedical applications, and the applied role of nanohydrogels in the construction of advanced therapeutics. We reviewed recent studies on nanohydrogels for their wide applications in building strategies for advantageously controlled biological applications. The classification of polymers is based on their sources of origin. Nanohydrogel studies are based on their polymeric types and their endorsed utilization for reported applications. Nanotechnology has developed significantly in the past decades. The novel and active role of nano biomaterials with amplified aspects are consistently being studied to minimize the deleterious practices and side effects. Here, we put forth challenges and discuss the outlook regarding the role of nanohydrogels, with future perspectives on delivering constructive strategies and overcoming the critical objectives in nanotherapeutic systems.
在纳米技术时代,用于先进应用的纳米材料的合成得到了极大的发展。使用纳米载体对有效的药物进行有效的治疗和功能化被认为是非常有成效和选择性必需的。聚合物纳米材料在这个过程中表现出了其影响力和重要作用。由于其低细胞毒性行为、强大的功能化以及对体外和体内治疗的实际方法,聚合物纳米材料在分子科学中得到了很好的应用。本综述简要讨论了纳米水凝胶设计、生物医学应用中最近使用的技术,以及纳米水凝胶在先进治疗方法构建中的应用作用。我们综述了最近关于纳米水凝胶的研究,因为它们在构建有利控制生物应用的策略方面有广泛的应用。聚合物的分类基于它们的来源。纳米水凝胶的研究基于它们的聚合物类型及其在报道的应用中的应用。纳米技术在过去几十年中得到了显著发展。新型和活跃的纳米生物材料及其放大方面的作用一直在被研究,以尽量减少有害实践和副作用。在这里,我们提出了挑战,并讨论了关于纳米水凝胶作用的展望,以及在纳米治疗系统中提供建设性策略和克服关键目标的未来前景。