恶性黑色素瘤模拟真菌感染 1 例报告。
Malignant melanoma mimic fungal infection a case report.
机构信息
Department of Science and Technology, Anhui University of Chinese Medicine, 230038, Anhui Province, Hefei, P. R. China.
Department of Infectious Diseases, the First Affiliated Hospital of Anhui Medical University, Anhui Province, 230022, Hefei, P. R. China.
出版信息
Diagn Pathol. 2022 Feb 27;17(1):33. doi: 10.1186/s13000-022-01214-7.
BACKGROUND
Most of malignant melanomas originate from skin and often metastasize to the lungs, rarely metastasizes to the liver and bone. However, imageology characters of lung metastasis tumor are commonly similar to those of fungal infections.
CASE PRESENTATION
A patient was admitted with unhealed plantar puncture wound for 3 years, and cough and expectoration for 2 years. The chest computed tomography (CT) revealed multiple nodules with cavities, and the patient was diagnosed of pulmonary fungal infection in another hospital and received antifungal therapy for more than 8 months, but the clinical symptoms and chest imaging findings continue to progress. After admission, the pathological results of both lung biopsy and biopsy of the plantar wound 3 years ago indicated malignant melanoma.
CONCLUSIONS
The diagnosis of lung lesions cannot rely solely on imaging diagnosis, lung biopsy should be performed if necessary.
背景
大多数恶性黑色素瘤起源于皮肤，常转移至肺部，很少转移至肝脏和骨骼。然而，肺部转移瘤的影像学特征通常与真菌感染相似。
病例介绍
患者因足底刺伤未愈 3 年，咳嗽、咳痰 2 年入院。胸部计算机断层扫描（CT）显示多个有空腔的结节，患者在另一家医院被诊断为肺部真菌感染，并接受了超过 8 个月的抗真菌治疗，但临床症状和胸部影像学表现仍在持续进展。入院后，肺部活检和 3 年前足底伤口活检的病理结果均提示为恶性黑色素瘤。
结论
肺部病变的诊断不能仅依赖于影像学诊断，如果有必要，应进行肺部活检。
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