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红斑狼疮患者的声门:频闪喉镜特征。

Glottic in a patient with systemic lupus erythematosus: videolaryngostroboscopic characteristics.

机构信息

Department of Otorhinolarynology-Head and Neck Surgery, Faculty of Medicine, Universiti Kebangsaan Malaysia (UKM), Kuala Lumpur, Malaysia.

Department of Otorhinolarynology-Head and Neck Surgery, Faculty of Medicine, Universiti Kebangsaan Malaysia (UKM), Kuala Lumpur, Malaysia

出版信息

BMJ Case Rep. 2022 Feb 28;15(2):e245840. doi: 10.1136/bcr-2021-245840.

Abstract

Systemic lupus erythematous (SLE) is an autoimmune disease commonly treated with steroid which leads to immunosuppression and increased susceptibility to infection. Chronic laryngitis with whitish lesion on the true vocal fold in SLE may be caused by opportunistic organisms, such as tuberculous, fungal and infections. Videolaryngostroboscopy may be helpful in leading to the diagnosis and optimum treatment of glottic A woman in her 40s with SLE presented with progressively worsening hoarseness for 2 months, accompanied by sore throat and odynophagia. Videoendoscopy showed erythematous and oedematous bilateral vocal fold with whitish lesion seen at the edge of middle one-third while the videolaryngostroboscopic evaluation showed there was severe asymmetry of the bilateral vocal folds, with severely reduced amplitude during phonation where the vocal cords were not vibrating, aperiodic vibratory cycles and 'always open', incomplete closure of vocal cord pattern. Later, endolaryngeal microsurgery and biopsy of the lesion confirmed of glottic Her symptoms and followed up videolaryngostroboscopy showed resolution to normal findings after 6 weeks of cloxacillin. infection of the glottis is a differential diagnosis in a chronic laryngitis with leucoplakic lesion in an immunosuppressive patient. Videolaryngostroboscopy has an important role in diagnosis, evaluation and treatment decision.

摘要

系统性红斑狼疮(SLE)是一种自身免疫性疾病,通常用类固醇治疗,这会导致免疫抑制和增加感染的易感性。SLE 患者的真声带出现白色病变的慢性喉炎可能是由机会性生物体引起的,如结核、真菌和 感染。频闪喉镜检查有助于诊断和优化声门 一位 40 多岁的女性患有 SLE,出现进行性加重的声音嘶哑 2 个月,伴有咽痛和吞咽困难。视频内镜检查显示双侧声带红斑和水肿,中三分之一边缘可见白色病变,频闪喉镜检查显示双侧声带严重不对称,发音时声带振幅严重降低,周期性振动周期和“总是开放”,声带闭合不完全。随后,经内喉显微手术和病变活检证实为声门 感染。在免疫抑制患者中,慢性喉炎伴白色斑块病变时,需要鉴别诊断 感染。频闪喉镜检查在诊断、评估和治疗决策中具有重要作用。

在经过 6 周的氯唑西林治疗后,她的症状和后续频闪喉镜检查显示正常。

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本文引用的文献

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Acute infectious laryngitis: A case series.急性感染性喉炎:病例系列
Ear Nose Throat J. 2018 Sep;97(9):306-313. doi: 10.1177/014556131809700920.
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Factors Associated With Infectious Laryngitis: A Retrospective Review of 15 Cases.与感染性喉炎相关的因素:15例回顾性分析
Ann Otol Rhinol Laryngol. 2017 May;126(5):388-395. doi: 10.1177/0003489417694911. Epub 2017 Feb 1.
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Bacterial biofilm associated with chronic laryngitis.与慢性喉炎相关的细菌生物膜。
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Systemic lupus erythematosus.系统性红斑狼疮
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