Nikniaz Zeinab, Mahdavi Reza, Akhavan Sabbagh Mojgan, Nikniaz Leila, Shirmohammadi Masood
Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Nutrition Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
BMC Nutr. 2022 Mar 1;8(1):18. doi: 10.1186/s40795-022-00512-z.
In the present study, we assessed the dietary acid load in adult celiac patients and compared it with that of the healthy population to provide more specific dietary recommendations for celiac patients.
This study was a cross-sectional study that included 130 celiac patients and 462 Non-celiac participants. The 80-item semi-quantitative food frequency questionnaire was used to obtain dietary data. Based on the dietary data, the dietary acid load (DAL), Potential renal net acid load (PRAL), and net endogenous acid production (NEAP) were calculated.
The mean PRAL value is negative in the celiac group but positive in the general population. There was a significant difference in the PRAL score between celiac patients and the general population (p < 0.001). The mean NEAP and DAL score were significantly lower in the celiac group compared with the healthy population (P < 0.001). There were no significant differences between gluten-free diet adherents and non-adherents regarding the PRAL, NEAP, and DAL values (P > 0.05).
We showed that the patients with celiac disease had a significantly less acidogenic diet compared with that of the general population. So, following dies low in gluten may be associated with less acid production spacially in populations at risk of acid/base imbalance.
在本研究中，我们评估了成年乳糜泻患者的膳食酸负荷，并将其与健康人群的膳食酸负荷进行比较，以便为乳糜泻患者提供更具体的饮食建议。
本研究为横断面研究，纳入了130例乳糜泻患者和462例非乳糜泻参与者。采用80项半定量食物频率问卷获取饮食数据。根据饮食数据，计算膳食酸负荷（DAL）、潜在肾净酸负荷（PRAL）和内源性酸净生成量（NEAP）。
乳糜泻组的平均PRAL值为负，而普通人群的平均PRAL值为正。乳糜泻患者与普通人群的PRAL评分存在显著差异（p < 0.001）。与健康人群相比，乳糜泻组的平均NEAP和DAL评分显著更低（P < 0.001）。在PRAL、NEAP和DAL值方面，坚持无麸质饮食者与未坚持者之间无显著差异（P > 0.05）。
我们发现，与普通人群相比，乳糜泻患者的产酸饮食显著更少。因此，对于有酸/碱失衡风险的人群，尤其是遵循低麸质饮食可能与较少的酸生成有关。
