Keiner Miriam, Dreller Vanessa, Klemm Isabelle, Lehmann Hendrik
Klinikum Veterinärmedizin, Klinik für Kleintiere, Innere Medizin, Justus-Liebig-Universität Gießen.
Tierarztl Prax Ausg K Kleintiere Heimtiere. 2022 Mar;50(1):46-56. doi: 10.1055/a-1696-3847. Epub 2022 Mar 2.
A 2-year old cross-breed dog presented due to acute vomiting and progressive lethargy following ingestion of the owner's anti-gout medication (colchicine, 0.35 mg/kg) 1-3 hours prior to presentation.The dog developed signs of all 3 stages of colchicine poisoning (gastrointestinal phase, multi-organ phase, recovery phase) and the clinical course was complicated by the presence of multi-organ dysfunction syndrome (MODS) and numerous negative prognostic factors.This case report describes the clinical and laboratory effects of colchicine poisoning and represents the first successful treatment of an accidental colchicine ingestion in a dog in Europe.
一只2岁的杂交犬在就诊前1 - 3小时摄入了主人的抗痛风药物(秋水仙碱,0.35毫克/千克),随后出现急性呕吐和进行性嗜睡而前来就诊。这只狗出现了秋水仙碱中毒所有三个阶段的症状(胃肠道阶段、多器官阶段、恢复阶段),临床过程因多器官功能障碍综合征(MODS)和众多不良预后因素而变得复杂。本病例报告描述了秋水仙碱中毒的临床和实验室影响,代表了欧洲首例成功治疗狗意外摄入秋水仙碱的案例。