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小脑脑桥角表皮样肿瘤的显微外科切除术。

Microsurgical Technique for Resection of a Cerebellopontine Angle Epidermoid Tumor.

机构信息

Department of Neurological Surgery, Mayo Clinic, Phoenix, Arizona, USA; Precision Neuro-therapeutics Innovation Laboratory, Mayo Clinic, Phoenix, Arizona, USA; Neurosurgery Simulation and Innovation Laboratory, Mayo Clinic, Phoenix, Arizona, USA.

Department of Otolaryngology, Mayo Clinic, Phoenix, Arizona, USA.

出版信息

World Neurosurg. 2022 Jun;162:6. doi: 10.1016/j.wneu.2022.02.026. Epub 2022 Mar 1.

Abstract

Epidermoid tumors are slow-growing, benign, congenital lesions. They commonly arise in the cerebellopontine angle, fourth ventricle, suprasellar region, or spinal cord. Symptoms may include hearing loss, facial pain, and headaches. The management options include observation or surgical resection. If the patient has symptoms, surgical resection is the treatment option of choice with the goal of gross total resection. In Video 1, we discuss the microsurgical technique for the resection of a right cerebellopontine angle epidermoid tumor. A 22-year-old male patient presented with chronic headache, decreased right-sided hearing, right facial pain, and right facial twitching. Magnetic resonance imaging revealed the characteristic finding of an epidermoid tumor, which appeared as isointense on T1 and hyperintense on T2 with diffusion-weighted imaging. The patient was taken to the operating room, and a retrosigmoid craniotomy was performed on the basis of the transverse and sigmoid sinuses. The tumor capsule was opened, and the tumor was decompressed by removing the internal components consisting of epithelial keratin and cholesterol crystals, allowing for a gross total resection to be achieved. The patient's postoperative computed tomography scan showed no residual tumor, and the patient was discharged on postoperative day 1 in stable condition.

摘要

表皮样肿瘤生长缓慢,为良性先天性病变。它们通常发生在桥小脑角、第四脑室、鞍上区或脊髓。症状可能包括听力损失、面部疼痛和头痛。治疗方案包括观察或手术切除。如果患者有症状,手术切除是首选治疗方法,目的是实现大体全切除。在视频 1 中,我们讨论了切除右侧桥小脑角表皮样肿瘤的显微外科技术。一名 22 岁男性患者表现为慢性头痛、右侧听力下降、右侧面部疼痛和右侧面部抽搐。磁共振成像显示了表皮样肿瘤的特征性表现,在 T1 上呈等信号,在 T2 上呈高信号,弥散加权成像呈高信号。患者被送入手术室,根据横窦和乙状窦行枕下乙状窦后入路开颅术。切开肿瘤包膜,通过去除由上皮角蛋白和胆固醇晶体组成的内部成分来减压肿瘤,从而实现大体全切除。患者术后 CT 扫描未见残留肿瘤,术后第 1 天病情稳定出院。

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