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糖尿病择期手部手术中的糖化血红蛋白与感染:退伍军人事务医疗中心2012 - 2018年的经验

HbA1c and Infection in Diabetic Elective Hand Surgery: A Veterans Affair Medical Center Experience 2012-2018.

作者信息

Coady-Fariborzian Loretta, Anstead Christy

机构信息

Malcom Randall VA Medical Center, Gainesville, FL, USA.

University of Florida, Department of Surgery, Plastic Surgery Division, Gainesville, USA.

出版信息

Hand (N Y). 2023 Sep;18(6):994-998. doi: 10.1177/1558944720937363. Epub 2022 Mar 7.

Abstract

BACKGROUND

Hemoglobin A1c (HbA1c) is an indicator of glucose control over a 3-month period. The plastic surgery service began screening HbA1c levels prior to surgery when a trend in infectious complications was noted in diabetics. We made a cutoff value of < 8% for elective hand surgery.

METHODS

The institutional review board approved a 7-year retrospective chart review (#201900402) 2012 through 2018 of our elective diabetic hand surgery cases. Data collected included: surgery, HbA1c levels within 3 months before surgery, glucose finger sticks day of surgery, and infectious complications up to 30 days after surgery. A Fisher exact test using a value of < .05 and a logistic regression analysis using a value of < .05 were used to determine statistical significance between infectious complications and screening.

RESULTS

In all, 848 cases were recorded in the data base. Infection complication rates before and after screening were not statistically significant ( = .44). All major complications (3) requiring a return to the operating room involved surgery within the flexor sheath before screening was enforced. This was not statistically significant ( = .25). The relative risk of an infectious complication involving the flexor sheath in unscreened patients was 3.66. A logistic regression analysis found no correlation with infectious complications based on the 3 variables of screening time ( = .99), preoperative finger stick values ( = .12), or HbA1c levels ( = .29).

CONCLUSION

The data did not support our guidelines for enforcing HbA1c cutoff levels prior to elective hand surgery. Consider enforcing levels < 8% when the flexor sheath may be violated.

摘要

背景

糖化血红蛋白(HbA1c)是三个月期间血糖控制情况的一个指标。整形外科服务部门在注意到糖尿病患者感染并发症的一种趋势后,开始在手术前筛查HbA1c水平。我们为择期手部手术设定了一个<8%的临界值。

方法

机构审查委员会批准了一项对2012年至2018年择期糖尿病手部手术病例进行的为期7年的回顾性图表审查(#201900402)。收集的数据包括:手术、手术前3个月内的HbA1c水平、手术当天的血糖指尖检测结果以及术后30天内的感染并发症情况。使用p值<0.05的Fisher精确检验和p值<0.05的逻辑回归分析来确定感染并发症与筛查之间的统计学显著性。

结果

数据库中总共记录了848例病例。筛查前后的感染并发症发生率无统计学显著性差异(p = 0.44)。所有3例需要返回手术室的主要并发症都发生在强制筛查实施之前的屈肌鞘内手术中。这无统计学显著性差异(p = 0.25)。未筛查患者中涉及屈肌鞘的感染并发症的相对风险为3.66。逻辑回归分析发现,基于筛查时间(p = 0.99)、术前指尖检测值(p = 0.12)或HbA1c水平(p = 0.29)这三个变量,与感染并发症均无相关性。

结论

数据不支持我们在择期手部手术前强制实施HbA1c临界值水平的指南。当屈肌鞘可能被侵犯时,考虑实施<8%的水平。

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