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Cutaneous Transcriptomics Identifies Fibroproliferative and Neurovascular Gene Dysregulation in Prurigo Nodularis Compared with Psoriasis and Atopic Dermatitis.

作者信息

Sutaria Nishadh, Alphonse Martin Prince, Roh Youkyung S, Choi Justin, Parthasarathy Varsha, Deng Junwen, Bordeaux Zachary A, Taylor Matthew T, Pritchard Thomas, Kim Noori, Aguh Crystal, Semenov Yevgeniy R, Archer Nathan K, Garza Luis A, Kang Sewon, Kwatra Shawn G

机构信息

Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Department of Dermatology, Massachusetts General Hospital, Boston, Massachusetts, USA.

出版信息

J Invest Dermatol. 2022 Sep;142(9):2537-2540. doi: 10.1016/j.jid.2022.02.010. Epub 2022 Mar 4.

Abstract
摘要

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A Nationwide Study of Prurigo Nodularis: Disease Burden and Healthcare Utilization in the United States.
J Invest Dermatol. 2021 Oct;141(10):2530-2533.e1. doi: 10.1016/j.jid.2021.02.756. Epub 2021 Apr 3.
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Prurigo Nodularis Is Characterized by Systemic and Cutaneous T Helper 22 Immune Polarization.
J Invest Dermatol. 2021 Sep;141(9):2208-2218.e14. doi: 10.1016/j.jid.2021.02.749. Epub 2021 Mar 23.
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Prurigo nodularis: Epidemiology and clinical features.
J Am Acad Dermatol. 2020 Dec;83(6):1559-1565. doi: 10.1016/j.jaad.2020.04.183. Epub 2020 May 23.
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Phase 2 randomized, double-blind study of IL-17 targeting with secukinumab in atopic dermatitis.
J Allergy Clin Immunol. 2021 Jan;147(1):394-397. doi: 10.1016/j.jaci.2020.04.055. Epub 2020 May 16.
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Short-term transcriptional response to IL-17 receptor-A antagonism in the treatment of psoriasis.
J Allergy Clin Immunol. 2020 Mar;145(3):922-932. doi: 10.1016/j.jaci.2019.10.041. Epub 2019 Dec 27.
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Nuclear localization of activated STAT6 and STAT3 in epidermis of prurigo nodularis.
Br J Dermatol. 2011 Nov;165(5):990-6. doi: 10.1111/j.1365-2133.2011.10498.x. Epub 2011 Sep 29.

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