Department of Ophthalmology, University of Muenster Medical Center, Albert-Schweitzer-Campus 1, Building D15, 48149, Muenster, Germany.
Department of Ophthalmology, Fulda Medical Center, Fulda, Germany.
Graefes Arch Clin Exp Ophthalmol. 2022 Sep;260(9):3087-3093. doi: 10.1007/s00417-022-05598-6. Epub 2022 Mar 8.
To evaluate the utility of intraocular lens (IOL) power calculation using adjusted conventional keratometry (K) according to postoperative posterior to preoperative anterior corneal curvature radii (PPPA) ratio for eyes with Fuch's dystrophy undergoing cataract surgery combined with Descemet membrane endothelial keratoplasty (triple DMEK).
A fictitious refractive index (FRI) was determined (Pentacam HR®) based on the PPPA ratio in 50 eyes undergoing triple DMEK. Adjusted corneal power was calculated in every eye using adjusted K values: K values determined by the IOLMaster were converted to adjusted anterior corneal radius using the mean FRI. Posterior corneal radius was calculated using the mean PPPA ratio. Adjusted corneal power was determined based on the calculated corneal radii and thick lens formula. Refractive errors calculated using the Haigis, SRK/T, and HofferQ formulae based on the adjusted corneal power were compared with those based on conventional K measurements.
Calculated PPPA ratio and FRI were 0.801 and 1.3271. Mean prediction error based on conventional K was in the hyperopic direction (Haigis: 0.84D; SRK/T: 0.74D; HofferQ: 0.74D) and significantly higher (P < 0.001) than that based on adjusted corneal power (0.18D, 0.22D, and 15D, respectively). When calculated according to adjusted corneal power, the percentage of eyes with a hyperopic shift > 0.5D fell significantly from 64 to 30% (Haigis), 62 to 36% (SRK/T), and 58 to 26% (HofferQ), respectively.
IOL power calculation based on adjusted corneal power can be used to reduce the risk of a hyperopic shift after triple DMEK and provides a more accurate refractive outcome than IOL power calculation using conventional K.
评估在患有 Fuch 角膜营养不良的患者中,白内障手术联合 Descemet 膜内皮角膜移植术(三重 DMEK)后,根据术后前角膜曲率半径与术前前角膜曲率半径的比值(PPPA),使用调整后的常规角膜曲率计(K)计算人工晶状体(IOL)屈光度的效用。
对 50 例行三重 DMEK 的患者的 PPPA 比值进行了虚构折射率(FRI)的确定(Pentacam HR®)。在每只眼中,使用调整后的 K 值计算调整后的角膜屈光力:通过 IOLMaster 确定的 K 值通过平均 FRI 转换为调整后的前角膜半径。后角膜半径通过平均 PPPA 比值计算。根据计算出的角膜半径和厚透镜公式确定调整后的角膜屈光力。根据调整后的角膜屈光力计算出的屈光度误差与根据常规 K 测量值计算出的屈光度误差进行比较,使用 Haigis、SRK/T 和 HofferQ 公式。
计算出的 PPPA 比值和 FRI 分别为 0.801 和 1.3271。基于常规 K 的平均预测误差为远视方向(Haigis:0.84D;SRK/T:0.74D;HofferQ:0.74D),且显著更高(P < 0.001),与基于调整后的角膜屈光力的预测误差(0.18D、0.22D 和 15D)相比。根据调整后的角膜屈光力计算时,远视偏移量大于 0.5D 的眼的百分比从 64%显著下降至 30%(Haigis)、62%下降至 36%(SRK/T)和 58%下降至 26%(HofferQ)。
基于调整后的角膜屈光力计算 IOL 屈光度可以降低三重 DMEK 后远视漂移的风险,并提供比使用常规 K 计算 IOL 屈光度更准确的屈光结果。