偏头痛：关于其历史、全球流行病学、危险因素及合并症的综述
Migraine: A Review on Its History, Global Epidemiology, Risk Factors, and Comorbidities.
作者信息
Amiri Parastoo, Kazeminasab Somayeh, Nejadghaderi Seyed Aria, Mohammadinasab Reza, Pourfathi Hojjat, Araj-Khodaei Mostafa, Sullman Mark J M, Kolahi Ali-Asghar, Safiri Saeid
机构信息
Research Center for Integrative Medicine in Aging, Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran.
Research Deputy, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
出版信息
Front Neurol. 2022 Feb 23;12:800605. doi: 10.3389/fneur.2021.800605. eCollection 2021.
Abstract
Migraine affects more than one billion individuals each year across the world, and is one of the most common neurologic disorders, with a high prevalence and morbidity, especially among young adults and females. Migraine is associated with a wide range of comorbidities, which range from stress and sleep disturbances to suicide. The complex and largely unclear mechanisms of migraine development have resulted in the proposal of various social and biological risk factors, such as hormonal imbalances, genetic and epigenetic influences, as well as cardiovascular, neurological, and autoimmune diseases. This review presents a comprehensive review of the most up-to-date literature on the epidemiology, and risk factors, as well as highlighting the gaps in our knowledge.
摘要
偏头痛每年在全球影响着超过10亿人，是最常见的神经系统疾病之一，具有高患病率和发病率，尤其在年轻人和女性中。偏头痛与多种合并症相关，范围从压力和睡眠障碍到自杀。偏头痛发展的复杂且很大程度上尚不清楚的机制导致了各种社会和生物学风险因素的提出，如激素失衡、遗传和表观遗传影响，以及心血管、神经和自身免疫性疾病。本综述全面回顾了关于流行病学和风险因素的最新文献，并突出了我们知识中的空白。
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