血浆ω-3与中青年个体的四肢肌肉质量指数无关：2011 - 2012年美国国家健康与营养检查调查结果
Plasma omega-3 is not associated with appendicular muscle mass index in young and middle-aged individuals: Results from NHANES 2011-2012.
作者信息
de Branco Flávia M S, Rossato Luana T, Rinaldi Ana Elisa M, Azeredo Catarina M, de Oliveira Erick P
机构信息
Laboratory of Nutrition, Exercise and Health (LaNES), School of Medicine, Federal University of Uberlandia (UFU), Uberlandia, Minas Gerais, Brazil.
School of Medicine, Federal University of Uberlandia (UFU), Uberlandia, Minas Gerais, Brazil.
出版信息
Prostaglandins Leukot Essent Fatty Acids. 2022 Mar;178:102412. doi: 10.1016/j.plefa.2022.102412. Epub 2022 Mar 4.
The aim of this study was to evaluate the association between plasma omega-3 (ω-3) and appendicular muscle mass index (AMMI) in young and middle-aged individuals; and also to evaluate whether these associations are sex-specific. A cross-sectional study was performed evaluating 1037 individuals aged 20 to 59 years from a sub-sample of the National Health and Nutrition Examination Survey (NHANES) 2011-2012. Plasma ω-3 was evaluated by gas chromatography-mass spectrometry and lean mass was assessed by dual-energy x-ray absorptiometry (DXA). Total plasma ω-3, docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA) and alpha-linolenic acid (ALA) were not associated with AMMI in total sample, men and women after adjustments for confounders. Plasma ω-3 and its subtypes were not associated with AMMI in a subanalysis evaluating young (20 to 44 y) and middle-aged (45 to 59 y) individuals separately. In conclusion, plasma ω-3 fatty acids are not associated with AMMI in young and middle-aged individuals regardless of sex.
本研究的目的是评估血浆ω-3（ω-3）与青年和中年个体的四肢肌肉质量指数（AMMI）之间的关联；并评估这些关联是否具有性别特异性。进行了一项横断面研究，对来自2011 - 2012年国家健康与营养检查调查（NHANES）子样本的1037名年龄在20至59岁之间的个体进行了评估。通过气相色谱 - 质谱法评估血浆ω-3，通过双能X线吸收法（DXA）评估瘦体重。在对混杂因素进行调整后，总样本、男性和女性的血浆总ω-3、二十二碳六烯酸（DHA）、二十碳五烯酸（EPA）和α-亚麻酸（ALA）与AMMI均无关联。在分别评估青年（20至44岁）和中年（45至59岁）个体的亚分析中，血浆ω-3及其亚型与AMMI均无关联。总之，无论性别如何，血浆ω-3脂肪酸与青年和中年个体的AMMI均无关联。
Zotero 插件