Pipoyan Davit, Hovhannisyan Astghik, Beglaryan Meline, Mantovani Alberto
Center for Ecological-Noosphere Studies of NAS RA, Armenia.
National Institute of Health, Rome, Italy.
Food Chem Toxicol. 2022 May;163:112922. doi: 10.1016/j.fct.2022.112922. Epub 2022 Mar 15.
The study aimed to investigate the potentially toxic trace elements (PTEs) Pb, Cd, Hg, Mo, and Cu in dairy products sold in Yerevan's markets and to assess the related exposure and possible health risks among the adult population residing in the capital city of Armenia, Yerevan. The PTEs contents were determined in widely consumed dairy products (pasteurized milk, sour cream, matsoun and cheese from cow milk) using graphite furnace atomic absorption spectrometry. PTE contents were in the range of 7.90E-04 (Pb in pasteurized milk) to 6.75E-01 (Cu in cheese) mg/kg. Food consumption was assessed by the 24-h dietary recall method. The PTE daily intakes and margin of exposure (MOE) were calculated by the deterministic approach. The results indicated potential health concerns for the contribution of dairy products to the overall dietary intake of Pb and Cd. MOEs of Pb and Cd (8.71 and 8.80, respectively) estimated for high consumers of cheese (90 g/day and more) were lower than 10. The pilot data set provides the first comprehensive appraisal on the dairy products contamination by PTEs in the Caucasus region. The results point out further attention to sources of Pb and Cd in Armenian dairy products, including environment and farm characteristics.
该研究旨在调查埃里温市场上销售的乳制品中潜在有毒微量元素(PTEs)铅(Pb)、镉(Cd)、汞(Hg)、钼(Mo)和铜(Cu)的含量,并评估亚美尼亚首都埃里温成年居民的相关暴露情况及可能的健康风险。采用石墨炉原子吸收光谱法测定了广泛消费的乳制品(巴氏杀菌牛奶、酸奶油、马祖恩奶酪和牛奶制成的奶酪)中的PTEs含量。PTEs含量范围为7.90E - 04(巴氏杀菌牛奶中的Pb)至6.75E - 01(奶酪中的Cu)mg/kg。通过24小时膳食回顾法评估食物摄入量。采用确定性方法计算PTEs的每日摄入量和暴露边际(MOE)。结果表明,乳制品对铅和镉总体膳食摄入量的贡献可能存在健康问题。奶酪高消费者(每天90克及以上)估计的铅和镉的MOE(分别为8.71和8.80)低于10。该试点数据集首次对高加索地区乳制品中PTEs污染情况进行了全面评估。结果指出,需要进一步关注亚美尼亚乳制品中铅和镉的来源,包括环境和农场特征。