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自体骨髓移植后转移性间质性肺炎。是恶性细胞回注的结果吗?

Metastatic interstitial pneumonitis after autologous bone marrow transplantation. A consequence of reinjection of malignant cells?

作者信息

Glorieux P, Bouffet E, Philip I, Biron P, Holzapfel L, Floret D, Bouvier R, Vitrey D, Pinkerton R, Brunat-Mentigny M

出版信息

Cancer. 1986 Nov 1;58(9):2136-9. doi: 10.1002/1097-0142(19861101)58:9<2136::aid-cncr2820580929>3.0.co;2-j.

Abstract

Two cases of fatal interstitial pneumonitis developing after an autologous bone marrow transplantation are described. In both cases the autopsy revealed diffuse malignant pulmonary involvement. The first case involved a 4-year-old boy who had a Burkitt's lymphoma; the second case involved a 4-year-old girl with a neuroblastoma. The authors postulate that in these cases, the clinical picture may have been related to reinfusion of malignant cells.

摘要

本文描述了两例自体骨髓移植后发生致命性间质性肺炎的病例。两例尸检均显示有弥漫性恶性肺部浸润。第一例为一名患有伯基特淋巴瘤的4岁男孩;第二例为一名患有神经母细胞瘤的4岁女孩。作者推测,在这些病例中,临床表现可能与恶性细胞的回输有关。

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