Kamath Sowmya, Kappaganthu Karthik, Painter Stefanie, Madan Anmol
Teladoc Health, Purchase, NY, United States.
JMIR Form Res. 2022 Mar 21;6(3):e33329. doi: 10.2196/33329.
Diabetes management is complex, and program personalization has been identified to enhance engagement and clinical outcomes in diabetes management programs. However, 50% of individuals living with diabetes are unable to achieve glycemic control, presenting a gap in the delivery of self-management education and behavior change. Machine learning and recommender systems, which have been used within the health care setting, could be a feasible application for diabetes management programs to provide a personalized user experience and improve user engagement and outcomes.
This study aims to evaluate machine learning models using member-level engagements to predict improvement in estimated A and develop personalized action recommendations within a remote diabetes monitoring program to improve clinical outcomes.
A retrospective study of Livongo for Diabetes member engagement data was analyzed within five action categories (interacting with a coach, reading education content, self-monitoring blood glucose level, tracking physical activity, and monitoring nutrition) to build a member-level model to predict if a specific type and level of engagement could lead to improved estimated A for members with type 2 diabetes. Engagement and improvement in estimated A can be correlated; therefore, the doubly robust learning method was used to model the heterogeneous treatment effect of action engagement on improvements in estimated A.
The treatment effect was successfully computed within the five action categories on estimated A reduction for each member. Results show interaction with coaches and self-monitoring blood glucose levels were the actions that resulted in the highest average decrease in estimated A (1.7% and 1.4%, respectively) and were the most recommended actions for 54% of the population. However, these were found to not be the optimal interventions for all members; 46% of members were predicted to have better outcomes with one of the other three interventions. Members who engaged with their recommended actions had on average a 0.8% larger reduction in estimated A than those who did not engage in recommended actions within the first 3 months of the program.
Personalized action recommendations using heterogeneous treatment effects to compute the impact of member actions can reduce estimated A and be a valuable tool for diabetes management programs in encouraging members toward actions to improve clinical outcomes.
糖尿病管理十分复杂,已确定方案个性化可提高糖尿病管理项目中的参与度和临床效果。然而,50%的糖尿病患者无法实现血糖控制,这表明在自我管理教育和行为改变的提供方面存在差距。已在医疗环境中使用的机器学习和推荐系统,可能是糖尿病管理项目的一种可行应用,以提供个性化的用户体验并提高用户参与度和效果。
本研究旨在评估使用会员级参与度的机器学习模型,以预测估计的A值的改善情况,并在远程糖尿病监测项目中制定个性化行动建议,以改善临床效果。
对Livongo糖尿病会员参与度数据进行回顾性研究,分析了五个行动类别(与教练互动、阅读教育内容、自我监测血糖水平、跟踪身体活动和监测营养),以建立一个会员级模型,预测特定类型和水平的参与度是否能使2型糖尿病患者的估计A值得到改善。参与度和估计A值的改善可能相关;因此,使用双重稳健学习方法对行动参与度对估计A值改善的异质治疗效果进行建模。
成功计算了五个行动类别中每个会员估计A值降低的治疗效果。结果显示,与教练互动和自我监测血糖水平是导致估计A值平均降幅最大的行动(分别为1.7%和1.4%),也是54%的人群最推荐的行动。然而,发现这些行动并非对所有会员都是最佳干预措施;预计46%的会员采用其他三种干预措施之一会有更好的结果。在项目的前三个月内,采取推荐行动的会员估计A值平均降幅比未采取推荐行动的会员大0.8%。
使用异质治疗效果来计算会员行动影响的个性化行动建议可以降低估计的A值,并且对于糖尿病管理项目而言,是鼓励会员采取行动改善临床效果的有价值工具。