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颈椎融合术——一名接受血液透析的慢性肾脏病患者中伪装成骨质疏松症的矿物质和骨代谢紊乱:病例报告

Cervical Fusion-Requiring Mineral and Bone Disorder Disguised as Osteoporosis in a Chronic Kidney Disease Patient on Hemodialysis: A Case Report.

作者信息

Lee Jong Weon, Cho Suhyun, Kim Kyung-Min, Park Jung Hyun

机构信息

Department of Physical Medicine and Rehabilitation, National Health Insurance Service Ilsan Hospital, Goyang, Korea.

Department and Research Institute of Rehabilitation of Medicine, Yonsei University College of Medicine, Seoul, Korea.

出版信息

J Bone Metab. 2022 Feb;29(1):59-62. doi: 10.11005/jbm.2022.29.1.59. Epub 2022 Feb 28.

Abstract

Bony deformities and fragility fractures in end-stage renal disease (ESRD) patients on long-term hemodialysis can be caused by either osteoporosis or chronic kidney disease-mineral and bone disorder (CKD-MBD). Correct identification of the underlying mechanism is critical since the treatment methods differ, and one treatment approach could negatively affect the other. Cervical kyphosis, severe enough to require immediate surgical treatment, can be caused by uncontrolled CKD-MBD, albeit in limited cases. This report presents the case of a 61-year-old female with an 11-year history of hemodialysis treatment and severe cervical kyphosis with myelopathy, which required 2-stage spinal surgeries. Our report calls for a careful diagnostic approach in ESRD patients with skeletal disorders, the points to consider before calcium replacement, and early detection of fragility fractures in them. Moreover, early mobilization and weight-bearing after the surgical procedure may lead to better neurological and functional improvements.

摘要

长期接受血液透析的终末期肾病(ESRD)患者出现骨畸形和脆性骨折,可能是由骨质疏松症或慢性肾脏病 - 矿物质和骨代谢紊乱(CKD - MBD)引起的。正确识别潜在机制至关重要,因为治疗方法不同,且一种治疗方法可能会对另一种产生负面影响。严重到需要立即进行手术治疗的颈椎后凸,尽管病例有限,但可能由未得到控制的CKD - MBD引起。本报告介绍了一名61岁女性的病例,该患者有11年血液透析治疗史,患有严重颈椎后凸并伴有脊髓病,需要进行两阶段脊柱手术。我们的报告呼吁对患有骨骼疾病的ESRD患者采取谨慎的诊断方法,补钙前需要考虑的要点,以及对他们的脆性骨折进行早期检测。此外,手术后早期活动和负重可能会带来更好的神经功能和功能改善。

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