Gać Paweł, Cheładze Przemysław, Poręba Rafał
Centre for Diagnostic Imaging, 4th Military Hospital, Weigla 5, PL 50-981 Wroclaw, Poland.
Department of Population Health, Division of Environmental Health and Occupational Medicine, Wroclaw Medical University, Mikulicza-Radeckiego 7, PL 50-368 Wroclaw, Poland.
Diagnostics (Basel). 2022 Mar 9;12(3):667. doi: 10.3390/diagnostics12030667.
Mitral annular calcification (MAC) is a common pathology of the mitral valve. In rare cases, calcifications occur in the mitral annulus degenerate serous; the caseous calcification of the mitral annulus (CCMA) then develops. Detection of CCMA is often random and requires differentiation from heart tumors or an abscess. The paper presents two cases of patients with ambiguous focal lesions of the mitral valve in echocardiography. In the first case, the cardiac computed tomography (CCT) showed a spherical, slightly irregular structure measuring approximately 33 × 22 mm, which was in contact with the posterior mitral valve leaflet from the lumen of the left ventricle. The lesion was heterogeneously intense, with an average density of about 500 HU and up to 975 HU on the periphery; it was not enhanced after the administration of a contrast agent. In the second case, the CCT revealed a heterogeneous, highly calcified structure in the peripheral zone and intermediate density in the central zone in the topography of the posterior mitral valve leaf, with dimensions up to about 41 × 31 mm in the plane of the valve leaflet, passing into the lumen of the left ventricle along its inferolateral wall to a depth of about 3.5 cm. In both cases, CCT enabled the diagnosis of CCMA. In conclusion, cardiac computed tomography may be decisive in the case of suspected caseous calcification of the mitral annulus where there is ambiguous echocardiography.
二尖瓣环钙化(MAC)是二尖瓣的一种常见病变。在罕见情况下,二尖瓣环会出现浆液性退变钙化,进而发展为二尖瓣环干酪样钙化(CCMA)。CCMA的检测往往具有偶然性,且需要与心脏肿瘤或脓肿相鉴别。本文报道了两例超声心动图检查显示二尖瓣局灶性病变不明确的患者。在第一例中,心脏计算机断层扫描(CCT)显示一个球形、略不规则的结构,大小约为33×22mm,从左心室腔与二尖瓣后叶接触。该病变密度不均匀,平均密度约为500HU,周边高达975HU;注射造影剂后无强化。在第二例中,CCT显示在二尖瓣后叶区域周边为不均匀、高度钙化的结构,中央区域为中等密度,在瓣叶平面尺寸达约41×31mm,沿其下外侧壁延伸至左心室腔约3.5cm深处。在这两例中,CCT均确诊为CCMA。总之,当超声心动图不明确时,心脏计算机断层扫描对于疑似二尖瓣环干酪样钙化的病例可能具有决定性作用。