Division of Infectious Diseases, Department of Pediatrics, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America.
Center for Health Promotion and Health Equity, School of Public Health, Brown University, Providence, Rhode Island, United States of America.
PLoS One. 2022 Apr 7;17(4):e0266692. doi: 10.1371/journal.pone.0266692. eCollection 2022.
Influenza is a major cause of morbidity and mortality worldwide. The flu vaccine is the most important strategy to prevent influenza. Studies indicate that individuals with mental health disorders are at an increased risk of comorbid health conditions that predispose them to severe flu complications. This study examined the association between mental distress and influenza vaccine coverage among non-institutionalized adults in the United States. Data was analyzed from the 2016 Behavioral Risk Factor Surveillance System (BRFSS). The analytic sample (453,924) included those with valid information on health-related quality of life (HRQOL) and flu vaccine coverage. Bivariate analysis and logistic regression were performed. Those with infrequent mental distress had 1% (95% confidence interval [CI] 0.96,1.03) lower odds and those with frequent mental distress had 21% (95% CI 0.75,0.82) decrease odds of receiving the flu shot in comparison to those with no mental distress, given all else equal. A negative effect on influenza vaccination rates was observed with frequent mental distress when compared to those with no mental distress. Further studies are warranted to better understand this association.
流感是全球发病率和死亡率的主要原因。流感疫苗是预防流感的最重要策略。研究表明,患有精神健康障碍的个体患合并症的风险增加,使他们易患严重的流感并发症。本研究在美国非住院成年人中调查了精神困扰与流感疫苗接种率之间的关系。数据分析来自 2016 年行为风险因素监测系统(BRFSS)。分析样本(453924 人)包括具有健康相关生活质量(HRQOL)和流感疫苗接种率有效信息的个体。进行了双变量分析和逻辑回归。与无精神困扰的个体相比,精神困扰不频繁的个体接种流感疫苗的几率低 1%(95%置信区间[CI]0.96,1.03),而精神困扰频繁的个体接种流感疫苗的几率降低 21%(95% CI 0.75,0.82),其他条件相同。与无精神困扰的个体相比,频繁的精神困扰对流感疫苗接种率有负面影响。需要进一步研究以更好地了解这种关联。