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影响体外冲击波碎石术(ESWL)结石清除率的因素:一项队列研究。

Factors influencing stone-free rate of Extracorporeal Shock Wave Lithotripsy (ESWL); a cohort study.

机构信息

Department of Clinical Sciences, Division of Infection Medicine, Lund University, Lund, Sweden.

Department of Urology Helsingborg Hospital, Helsingborg, Sweden.

出版信息

Scand J Urol. 2022 Jun;56(3):237-243. doi: 10.1080/21681805.2022.2055137. Epub 2022 Apr 9.

Abstract

OBJECTIVE

To evaluate the success rate of Extracorporeal Shock Wave Lithotripsy (ESWL) therapy and identify relevant treatment-specific factors affecting stone-free rate (SFR) after ESWL.

MATERIALS AND METHODS

All ESWL treatments in the years 2016-2019, in Ängelholm Hospital, Skåne, Sweden were analysed retrospectively. Primary outcome was stone-free rate (SFR) at 3 months. Univariate logistic regression was used followed by multivariable regression. Lasso analysis was made to adjust for treatment-specific factors such as age, stone size, skin-to-stone distance (SSD), stone attenuation, number of treatments, stone location and presence of a urinary stent.

RESULTS

Factors affecting successful ESWL treatment were lower age ( < 0.001), smaller stone size and volume (both  = 0.001). SSD, stone attenuation, sex, laterality and drainage did not have an effect on SFR in this study. After the first ESWL treatment session, 46.7% of the patients were stone-free.

CONCLUSION

Results indicate that stone size and age are the most predictive factors for ESWL outcome. Based on this, we present a simple model for prediction of SFR after ESWL, to be used when counseling patients before ESWL treatment.

摘要

目的

评估体外冲击波碎石术 (ESWL) 治疗的成功率,并确定影响 ESWL 后结石清除率 (SFR) 的相关治疗特异性因素。

材料与方法

对 2016 年至 2019 年期间在瑞典斯科讷省安格尔霍尔姆医院进行的所有 ESWL 治疗进行回顾性分析。主要结局是 3 个月时的结石清除率 (SFR)。采用单变量逻辑回归,然后进行多变量回归。进行套索分析以调整与治疗特异性相关的因素,如年龄、结石大小、皮肤至结石距离 (SSD)、结石衰减、治疗次数、结石位置和导尿管的存在。

结果

影响 ESWL 治疗成功的因素是年龄较小( < 0.001)、结石体积较小(均为  = 0.001)。SSD、结石衰减、性别、侧别和引流在本研究中对 SFR 没有影响。第一次 ESWL 治疗后,46.7%的患者结石清除。

结论

结果表明,结石大小和年龄是 ESWL 结果的最具预测性因素。基于此,我们提出了一种用于预测 ESWL 后 SFR 的简单模型,以便在 ESWL 治疗前为患者提供咨询。

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