新冠病毒感染人群中的中风发病率及预后
Stroke Incidence and Outcome in a Population With COVID-19.
作者信息
Alkhalifah Moayd M, Banda Ramzi, Alqudihy Shukri, Qureshi Shireen, Al-Tawfiq Jaffar A
机构信息
Neurology Unit, Neurosciences Institute, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia.
Hospital Medicine Department, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia.
出版信息
Neurohospitalist. 2022 Apr;12(2):213-217. doi: 10.1177/19418744211043323.
BACKGROUND AND PURPOSE
COVID-19 is associated with systemic thromboembolism including stroke. The study evaluated the 30-days stroke incidence in SARS-CoV-2 PCR positive patients and described the outcome of such patients.
METHODS
This is a retrospective study of consecutive patients with a positive SARS-CoV-2 PCR test between March 1st, 2020 and August 30th, 2020. The study included COVID-19 patients who were hospitalized and had a stroke within 30 days from the positive PCR test.
RESULTS
During the study period, there were 4301 patients with a positive SARS-CoV-2 PCR test. Of those, 1786 patients (41.5%) were hospitalized and 4 patients developed a stroke within 30 days. The 30-days stroke incidence was 0.09% and 0.2% of all and hospitalized patients, respectively. The mean age of stroke patients was 78 years and 2 died during the same hospitalization. The 4 patients had comorbidities, one had pre-existing atrial fibrillation and all had ischemic stroke.
CONCLUSION
This study showed a low 30-day incidence of stroke among COVID-19 patients.
背景与目的
新型冠状病毒肺炎（COVID-19）与包括中风在内的全身性血栓栓塞有关。本研究评估了严重急性呼吸综合征冠状病毒2（SARS-CoV-2）聚合酶链反应（PCR）检测呈阳性患者的30天中风发生率，并描述了此类患者的结局。
方法
这是一项对2020年3月1日至2020年8月30日期间SARS-CoV-2 PCR检测呈阳性的连续患者进行的回顾性研究。该研究纳入了COVID-19住院患者，且这些患者在PCR检测呈阳性后的30天内发生了中风。
结果
在研究期间，有4301例患者SARS-CoV-2 PCR检测呈阳性。其中，1786例患者（41.5%）住院，4例患者在30天内发生了中风。30天中风发生率在所有患者和住院患者中分别为0.09%和0.2%。中风患者的平均年龄为78岁，其中2例在同一住院期间死亡。这4例患者均有合并症，1例有既往房颤病史，所有患者均为缺血性中风。
结论
本研究显示COVID-19患者的30天中风发生率较低。
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