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重症肌无力与新型冠状病毒肺炎——临床困局

Myasthenia Gravis and COVID-19 - A Clinical Checkmate.

作者信息

Sivapurapu Vijayalakshmi, Natarajan Pratheeba, Bhat Ravindra Raghuveera, Remadevi R

机构信息

Department of Anaesthesiology and Critical Care, Indira Gandhi Medical College and Research Institute, Puducherry, India.

出版信息

Anesth Essays Res. 2021 Oct-Dec;15(4):457-459. doi: 10.4103/aer.aer_129_21. Epub 2022 Mar 8.

Abstract

Myasthenia gravis (MG) patients with coronavirus disease (COVID-19) pose a unique challenge for intensive care management. Higher risk of infection is observed in patients with MG due to the immunosuppressant medications they are prescribed. The underlying component of respiratory muscle weakness predisposes these patients to experience a more severe form of illness. In the case of diagnosis of COVID-19 in MG patients, judicious continuation of immunosuppressants, avoiding drugs that worsen MG along with the continuation of cholinesterase inhibitors is prudent. Early diagnosis in cases with high-index of suspicion, extra precautions, COVID-appropriate behavior, and early immunization is paramount for the health of MG patients during this pandemic.

摘要

患有冠状病毒病(COVID-19)的重症肌无力(MG)患者给重症监护管理带来了独特的挑战。由于所服用的免疫抑制药物,MG患者的感染风险更高。呼吸肌无力这一潜在因素使这些患者更容易患上更严重的疾病形式。对于MG患者诊断出COVID-19的情况,明智地继续使用免疫抑制剂、避免使用会加重MG的药物以及继续使用胆碱酯酶抑制剂是审慎的做法。对于高度怀疑的病例进行早期诊断、采取额外预防措施、遵循适合COVID的行为以及尽早接种疫苗,对于在此次大流行期间MG患者的健康至关重要。

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本文引用的文献

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