Orthopedics Department of Traditional Chinese Medicine, Taizhou Jiangyan Hospital of Traditional Chinese Medicine, Taizhou, China.
Comprehensive Nursing Clinic, PLA Rocket Force Characteristic Medical Center, Beijing, China.
J Healthc Eng. 2022 Apr 7;2022:9185384. doi: 10.1155/2022/9185384. eCollection 2022.
This study aimed for the analysis of the effect of acupuncture and moxibustion combined with needle-knife on pain and lumbar function in patients with lumbar disc herniation. From June 2019 to February 2021, the medical records of 126 patients with lumbar disc herniation admitted to the department of orthopedics of our hospital were selected and divided into the control group ( = 63) treated with acupuncture and moxibustion and the observation group ( = 63) treated with acupuncture and moxibustion combined with needle-knife according to different treatment regimens. After 4 weeks of treatment, the clinical efficacy, pain status, and lumbar function were compared between the two groups. The concentrations of relevant inflammatory factors (IL-6, IL-10, TNF-, and MMP-2) in peripheral blood of the two patients before and after treatment were measured by enzyme-linked immunosorbent assay (ELISA). After treatment, the overall response rate was 93.65% in the observation group, which was higher than 80.95% in the control group ( < 0.05); the visual blurred score (VAS) scores of lower limbs and waist in the observation group were lower than those in the control group, while the expression of pain mediators serotonin (5-HT) and prostaglandin E2 (PEG2) was also lower than that in the control group ( < 0.05); the Oswestry disability index (ODI) in the observation group was lower than that in the control group, while the Japanese Orthopedic Association assessment treatment score (JOA) was higher than that in the control group ( < 0.05). After treatment, the concentration levels in peripheral blood (IL-6, IL-10, TNF-, and MMP-2) were significantly lower in the observation group than in the control group ( < 0.05). Acupuncture and moxibustion combined with needle-knife is effective in the treatment of lumbar disc herniation, which helps to improve the clinical efficacy, relieve pain symptoms, promote the improvement of lumbar function, and contribute to the reduction of inflammatory factors.
本研究旨在分析针灸联合针刀治疗对腰椎间盘突出症患者疼痛和腰椎功能的影响。选取 2019 年 6 月至 2021 年 2 月我院骨科收治的腰椎间盘突出症患者 126 例的病历资料，根据不同治疗方案分为针灸对照组（n=63）和针灸联合针刀观察组（n=63）。治疗 4 周后，比较两组患者的临床疗效、疼痛状况和腰椎功能。采用酶联免疫吸附试验（ELISA）检测两组患者治疗前后外周血中相关炎症因子（IL-6、IL-10、TNF-和 MMP-2）的浓度。治疗后，观察组总有效率为 93.65%，高于对照组的 80.95%（<0.05）；观察组下肢和腰部视觉模拟评分（VAS）评分低于对照组，疼痛介质 5-羟色胺（5-HT）和前列腺素 E2（PEG2）的表达也低于对照组（<0.05）；观察组 Oswestry 功能障碍指数（ODI）低于对照组，日本矫形协会评估治疗评分（JOA）高于对照组（<0.05）。治疗后，观察组外周血（IL-6、IL-10、TNF-和 MMP-2）浓度水平明显低于对照组（<0.05）。针灸联合针刀治疗腰椎间盘突出症疗效确切，有助于提高临床疗效，缓解疼痛症状，促进腰椎功能改善，有助于降低炎症因子水平。
