Department of Cardiology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
Department of Internal Medicine, Respiratory Medicine Section, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
APMIS. 2022 Jul;130(7):397-403. doi: 10.1111/apm.13229. Epub 2022 May 16.
Aspergillomas are found in pre-existing cavities in pulmonary parenchyma. To the best of our knowledge, aspergilloma has not previously been reported in COVID-19-associated pulmonary architecture distortion combined with barotrauma from invasive mechanical ventilation therapy. We present a case of a 67-year-old woman, who suffered from severe COVID-19 in the summer of 2020 with no suspicion of infection with Aspergillus in the acute phase. Ten months after discharge from her COVID-related admission, she developed bilateral aspergillomas diagnosed by image diagnostics, bronchoscopy, and blood samples, and she now receives antifungal therapy. We would like to raise awareness on aspergilloma in post-COVID-19 patients, since it is an expected long-term complication to COVID-19 patients with pulmonary architectural distortion.
肺曲霉菌球是在肺实质的原有空洞中发现的。据我们所知,以前没有报道过 COVID-19 相关的肺结构扭曲合并侵袭性机械通气治疗引起的气压伤导致肺曲霉菌球。我们报告了一例 67 岁女性的病例,她在 2020 年夏季患有严重的 COVID-19,在急性期没有感染曲霉菌的迹象。在因 COVID-19 住院后 10 个月,她通过影像学诊断、支气管镜检查和血液样本诊断出双侧肺曲霉菌球,目前正在接受抗真菌治疗。我们想引起人们对 COVID-19 后患者肺曲霉菌球的认识,因为它是 COVID-19 患者中肺结构扭曲的一种预期的长期并发症。