孕早期胎儿肝动脉检查用于不良结局预测。
First-Trimester Fetal Hepatic Artery Examination for Adverse Outcome Prediction.
作者信息
Czuba Bartosz, Tousty Piotr, Cnota Wojciech, Borowski Dariusz, Jagielska Agnieszka, Dubiel Mariusz, Fuchs Anna, Fraszczyk-Tousty Magda, Dzidek Sylwia, Kajdy Anna, Świercz Grzegorz, Kwiatkowski Sebastian
机构信息
Department of Obstetrics and Gynecology, Medical University of Silesia, 41-703 Ruda Slaska, Poland.
Department of Gynecology and Obstetrics, Pomeranian Medical University, 70-111 Szczecin, Poland.
出版信息
J Clin Med. 2022 Apr 8;11(8):2095. doi: 10.3390/jcm11082095.
OBJECTIVE
To assess whether there are differences in first-trimester fetal hepatic artery flows depending on pregnancy outcomes.
METHODS
The prospective study conducted in 2012-2020 included 1841 fetuses from singleton pregnancies assessed during the routine first-trimester ultrasound examination (between 11- and 14-weeks' gestation). Also, each fetus was examined to determine their hepatic artery flows by measuring the artery's pulsatility index (HA-PI) and peak systolic velocity (HA-PSV).
RESULTS
The fetuses that were classified as belonging to the adverse pregnancy outcome group (those with karyotype abnormalities and congenital heart defects) were characterized by a significantly lower HA-PI and higher HA-PSV compared to normal outcome fetuses.
CONCLUSION
Hepatic artery flow assessment proved to be a very useful tool in predicting adverse pregnancy outcomes, in particular karyotype abnormalities and congenital heart defects.
目的
评估孕早期胎儿肝动脉血流是否因妊娠结局而异。
方法
2012年至2020年进行的前瞻性研究纳入了1841例单胎妊娠胎儿，这些胎儿在孕早期常规超声检查（妊娠11至14周）期间接受了评估。此外，对每个胎儿进行检查，通过测量肝动脉的搏动指数（HA-PI）和收缩期峰值速度（HA-PSV）来确定其肝动脉血流。
结果
与正常结局胎儿相比，被归类为不良妊娠结局组（染色体核型异常和先天性心脏缺陷胎儿）的胎儿具有显著更低的HA-PI和更高的HA-PSV。
结论
肝动脉血流评估被证明是预测不良妊娠结局，特别是染色体核型异常和先天性心脏缺陷的非常有用的工具。
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