School of Chemical Engineering, Sungkyunkwan University (SKKU), Suwon 16419, Republic of Korea.
Department of Biomedical Engineering, SKKU, Suwon 16419, Republic of Korea.
Science. 2022 May 6;376(6593):624-629. doi: 10.1126/science.abj9912. Epub 2022 May 5.
Bioelectronics needs to continuously monitor mechanical and electrophysiological signals for patients. However, the signals always include artifacts by patients' unexpected movement (such as walking and respiration under approximately 30 hertz). The current method to remove them is a signal process that uses a bandpass filter, which may cause signal loss. We present an unconventional bandpass filter material-viscoelastic gelatin-chitosan hydrogel damper, inspired by the viscoelastic cuticular pad in a spider-to remove dynamic mechanical noise artifacts selectively. The hydrogel exhibits frequency-dependent phase transition that results in a rubbery state that damps low-frequency noise and a glassy state that transmits the desired high-frequency signals. It serves as an adaptable passfilter that enables the acquisition of high-quality signals from patients while minimizing signal process for advanced bioelectronics.
生物电子学需要持续监测患者的机械和电生理信号。然而,这些信号总是包含患者意外运动(如行走和呼吸,大约在 30 赫兹以下)产生的伪迹。当前去除这些伪迹的方法是使用带通滤波器的信号处理,这可能会导致信号丢失。我们提出了一种非传统的带通滤波器材料——粘弹性明胶-壳聚糖水凝胶阻尼器,灵感来自于蜘蛛的粘弹性表皮垫,以有选择地去除动态机械噪声伪迹。该水凝胶表现出频率相关的相转变,导致橡胶状态阻尼低频噪声和玻璃态传输期望的高频信号。它作为一个适应性的滤波器,能够从患者身上获取高质量的信号,同时最大限度地减少信号处理,以实现先进的生物电子学。