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一种用于蛋白质高灵敏度检测的石墨烯/硅肖特基二极管。

A graphene/Si Schottky diode for the highly sensitive detection of protein.

作者信息

Noroozi Ali Akbar, Abdi Yaser

机构信息

Nanophysics Research Laboratory, Department of Physics, University of Tehran Tehran Iran

出版信息

RSC Adv. 2019 Jun 24;9(34):19613-19619. doi: 10.1039/c9ra03765a. eCollection 2019 Jun 19.

Abstract

Herein, a graphene/Si-based device was introduced for bovine serum albumin (BSA) sensing. In this study, it is shown that the Schottky junction at the interface of graphene/Si is highly sensitive to BSA under UV light exposure. The reverse bias current of the junction, which is sensitive to UV light, changes under exposure to BSA at different concentrations. By UV light absorption, we showed that the addition of the BSA solution to the junction affected the output characteristic of the fabricated device. Moreover, the output characteristic of the device shows that the device can be considered as a self-powered detector that would reduce the need for batteries. The results obtained in this study would open up a way towards the fabrication of an on-chip biosensor for the sensing of biological agents such as BSA.

摘要

在此,介绍了一种用于检测牛血清白蛋白(BSA)的基于石墨烯/硅的器件。在本研究中,结果表明,石墨烯/硅界面处的肖特基结在紫外光照射下对BSA高度敏感。该结的反向偏置电流对紫外光敏感,在暴露于不同浓度的BSA时会发生变化。通过紫外光吸收,我们表明向结中添加BSA溶液会影响所制备器件的输出特性。此外,该器件的输出特性表明,该器件可被视为一种自供电探测器,这将减少对电池的需求。本研究中获得的结果将为制造用于检测诸如BSA等生物制剂的片上生物传感器开辟一条道路。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f64/9065274/a1c449592bac/c9ra03765a-f5.jpg

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