在线与门诊自我报告日常认知量表的有效性。
Validity of Online Versus In-Clinic Self-Reported Everyday Cognition Scale.
机构信息
Taylor Howell, 4150 Clement Street, #114M Building 13 San Francisco, California 94121, USA, Telephone: 415-221-4810 x24222,
出版信息
J Prev Alzheimers Dis. 2022;9(2):269-276. doi: 10.14283/jpad.2022.20.
BACKGROUND
Online cognitive assessments are alternatives to in-clinic assessments.
OBJECTIVES
We evaluated the relationship between online and in-clinic self-reported Everyday Cognition Scale (ECog).
METHODS
In 94 Alzheimer's Disease Neuroimaging Initiative and Brain Health Registry (ADNI-BHR) participants, we estimated associations between online and in-clinic Everyday Cognition using Bland-Altman plots and regression. In 472 ADNI participants, we estimated reliability of in-clinic Everyday Cognition completed six months apart using Bland-Altman plots and regression.
RESULTS
Online Everyday Cognition associations: Mean difference was 0.11 (95% limits of agreement: -0.41 to 0.64). In-clinic Everyday Cognition score increased by 0.81 for each online Everyday Cognition score unit increase (R2=0.60). In-clinic Everyday Cognition reliability: Mean difference was 0.01 (95% limits of agreement: -0.61 to 0.62). In-clinic Everyday Cognition score at enrollment increased by 0.79 for each in-clinic Everyday Cognition score unit increase at six months (R2=0.61).
CONCLUSION
Online Everyday Cognition closely corresponded with in-clinic Everyday Cognition, supporting validity of using online cognitive assessments to more efficiently facilitate Alzheimer's disease research.
背景
在线认知评估是替代临床评估的方法。
目的
我们评估了在线和临床自我报告的日常认知量表（ECog）之间的关系。
方法
在 94 名阿尔茨海默病神经影像学倡议和大脑健康登记处（ADNI-BHR）参与者中，我们使用 Bland-Altman 图和回归估计了在线和临床日常认知之间的关联。在 472 名 ADNI 参与者中，我们使用 Bland-Altman 图和回归估计了相隔六个月的临床日常认知的可靠性。
结果
在线日常认知关联：平均差异为 0.11（95%置信区间：-0.41 至 0.64）。在线日常认知评分每增加 1 个单位，临床日常认知评分增加 0.81（R2=0.60）。临床日常认知可靠性：平均差异为 0.01（95%置信区间：-0.61 至 0.62）。在六个月时，临床日常认知评分在登记时每增加 0.79 个单位，临床日常认知评分就会增加（R2=0.61）。
结论
在线日常认知与临床日常认知密切相关，支持使用在线认知评估更有效地促进阿尔茨海默病研究的有效性。
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