Department of Obstetrics and Gynecology in Linköping, Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Department of Obstetrics and Gynecology in Norrköping, Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
BMC Pregnancy Childbirth. 2022 May 13;22(1):408. doi: 10.1186/s12884-022-04710-2.
The effects of diagnosing and treating labor dystocia with oxytocin infusion at different cervical dilatations have not been fully evaluated. Therefore, we aimed to examine whether cervical dilatation at diagnosis of dystocia and initiation of oxytocin infusion at different stages of cervical dilatation were associated with mode of birth, obstetric complications and women's birthing experience.
A retrospective cohort study, including 588 nulliparous term women with spontaneous onset of labor and dystocia requiring oxytocin augmentation. The study population was divided into three groups according to cervical dilatation at diagnosis of dystocia and initiation of oxytocin-infusion (≤ 5 cm, 6-10 cm, fully dilated) with mode of birth as the primary outcome. Secondary outcomes were obstetrical and neonatal complications and women´s experience of childbirth. Statistical comparison between groups using Chi-square and ANOVA was performed. The risk of operative birth (cesarean section and instrumental birth) was assessed using binary logistic regression with suitable adjustments (maternal age, body mass index and risk assessment on admission to the labor ward).
The cesarean section rate differed between the groups (p < 0.001); 12% in the ≤ 5 cm group, 6% in the 6-10 cm group and 0% in the fully dilated group. There was no increased risk for operative birth in the ≤ 5 cm group compared to the 6-10 cm group, adjusted OR 1.28 95%CI (0.78-2.08). The fully dilated group had a decreased risk of operative birth (adjusted OR 0.48 95%CI (0.27-0.85). The rate of a negative birthing experience was high in all groups (28.5%, 19% and 18%) but was only increased among women in the ≤ 5 cm group compared with the 6-10 cm group, adjusted OR 1.76 95%CI (1.05-2.95).
Although no difference in the risk of operative birth was found between the ≤ 5 cm and 6-10 cm cervical dilatation-groups, the cesarean section rate was highest in women with dystocia requiring oxytocin augmentation at ≤ 5 cm cervical dilatation. This might indicate that oxytocin augmentation before 6 cm cervical dilatation could be contra-productive in preventing cesarean sections. Further, the increased risk of negative birth experience in the ≤ 5 cm group should be kept in mind to improve labor care.
催产素输注在不同宫颈扩张程度下诊断和治疗产程延长的效果尚未得到充分评估。因此,我们旨在研究产程延长时的宫颈扩张程度和催产素输注开始时的宫颈扩张程度与分娩方式、产科并发症和女性分娩体验是否相关。
这是一项回顾性队列研究,纳入了 588 例初产妇,均为自发性临产且存在需催产素加强产程的产程延长。根据产程延长时的宫颈扩张程度和催产素输注开始时的宫颈扩张程度(≤5cm、6-10cm、完全扩张)将研究人群分为三组,以分娩方式为主要结局。次要结局为产科和新生儿并发症以及女性的分娩体验。使用卡方检验和方差分析对组间进行统计学比较。使用二元逻辑回归评估手术分娩(剖宫产和器械分娩)的风险,并进行适当调整(产妇年龄、体重指数和入院时的风险评估)。
不同组之间的剖宫产率不同(p<0.001);≤5cm 组为 12%,6-10cm 组为 6%,完全扩张组为 0%。与 6-10cm 组相比,≤5cm 组手术分娩的风险无增加,调整后的 OR 值为 1.28(95%CI:0.78-2.08)。完全扩张组手术分娩的风险降低(调整后的 OR 值为 0.48,95%CI:0.27-0.85)。所有组的负面分娩体验率都很高(28.5%、19%和 18%),但与 6-10cm 组相比,≤5cm 组的女性增加,调整后的 OR 值为 1.76(95%CI:1.05-2.95)。
尽管在≤5cm 和 6-10cm 宫颈扩张程度组之间未发现手术分娩风险存在差异,但在需要催产素加强产程的产程延长患者中,≤5cm 宫颈扩张程度的剖宫产率最高。这可能表明,在 6cm 宫颈扩张之前使用催产素可能会适得其反,反而增加剖宫产的风险。此外,应注意≤5cm 组中负面分娩体验风险的增加,以改善分娩护理。