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Forward single-cell sequencing into clinical application: Understanding of ageing and rejuvenation from clinical observation to single-cell solution.

作者信息

Yan Furong, Li Zhangping, Powell Charles A, Wang Xiangdong

机构信息

Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital, Fudan University Shanghai Medical College, Shanghai, China.

Shanghai Institute of Clinical Bioinformatics, Shanghai Engineering Research for AI Technology for Cardiopulmonary Diseases, Shanghai, China.

出版信息

Clin Transl Med. 2022 May;12(5):e827. doi: 10.1002/ctm2.827.

DOI:10.1002/ctm2.827
PMID:35593205
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9121316/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/692e/9121316/c667173ca7d4/CTM2-12-e827-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/692e/9121316/c667173ca7d4/CTM2-12-e827-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/692e/9121316/c667173ca7d4/CTM2-12-e827-g001.jpg

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Nature. 2022 Mar;603(7900):309-314. doi: 10.1038/s41586-022-04461-2. Epub 2022 Mar 2.
2
Melatonin enhances osteoblastogenesis of senescent bone marrow stromal cells through NSD2-mediated chromatin remodelling.褪黑素通过 NSD2 介导的染色质重塑增强衰老骨髓基质细胞的成骨作用。
Clin Transl Med. 2022 Feb;12(2):e746. doi: 10.1002/ctm2.746.
3
Clinical challenges of tissue preparation for spatial transcriptome.空间转录组学组织准备的临床挑战。
Clin Transl Med. 2022 Jan;12(1):e669. doi: 10.1002/ctm2.669.
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Spatial omics: Navigating to the golden era of cancer research.空间组学:迈向癌症研究的黄金时代。
Clin Transl Med. 2022 Jan;12(1):e696. doi: 10.1002/ctm2.696.
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Can single cell RNA sequencing reshape the clinical biochemistry of hematology: New clusters of circulating blood cells.单细胞 RNA 测序能否重塑血液学生化临床检验学:循环血细胞的新簇。
Clin Transl Med. 2021 Dec;11(12):e671. doi: 10.1002/ctm2.671.
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A cellular census of human peripheral immune cells identifies novel cell states in lung diseases.人类外周免疫细胞的细胞普查鉴定出肺部疾病中的新型细胞状态。
Clin Transl Med. 2021 Nov;11(11):e579. doi: 10.1002/ctm2.579.
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Activation of Ca -AMPK-mediated autophagy by ginsenoside Rg3 attenuates cellular senescence in human dermal fibroblasts.人参皂苷Rg3通过激活Ca-AMPK介导的自噬减轻人皮肤成纤维细胞的细胞衰老。
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