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大肠杆菌的抗菌药物耐药性及其对动物健康的危害。

Antimicrobial drug resistance against Escherichia coli and its harmful effect on animal health.

机构信息

Key Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture, Lanzhou, China.

Key Laboratory of New Animal Drug Project of Gansu Province, Lanzhou, China.

出版信息

Vet Med Sci. 2022 Jul;8(4):1780-1786. doi: 10.1002/vms3.825. Epub 2022 May 24.

Abstract

Multidrug resistance among pathogenic bacteria is imperilling the worth of antibiotic infection, which has become an emerging problem, which previously transformed the veterinary sciences. Since its discovery, many antibiotics have been effective in treating bacterial infections in animals. Escherichia coli, a bacterium, is one of the reservoirs of antibiotic resistance genes in a community. The current use of antibiotics and demographic factors usually increase multidrug resistance. Genetically, the continuous adoption of environmental changes by E. coli allows it to acquire many multidrug resistance. During the host's life, antimicrobial resistance rarely poses a threat to the E. coli strain and pressure, similar to that of a flexible animal lower intestine. In this review, we describe the E. coli antibiotic drug-resistance mechanism driving transmission, the causes of transmission and the harmful effects on animal health.

摘要

病原菌的多药耐药性正在危及抗生素感染的价值,这已成为一个新兴问题,它曾改变了兽医科学。自发现以来,许多抗生素在治疗动物的细菌感染方面非常有效。大肠杆菌是社区中抗生素耐药基因的储库之一。抗生素的当前使用和人口统计因素通常会增加多药耐药性。从遗传学上讲,大肠杆菌不断适应环境变化使其能够获得许多多药耐药性。在宿主的一生中,抗菌药物耐药性很少对大肠杆菌菌株和压力构成威胁,类似于灵活的动物下肠道。在本综述中,我们描述了推动传播的大肠杆菌抗生素耐药机制、传播的原因及其对动物健康的有害影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/224e/9297802/1360c8162964/VMS3-8-1780-g001.jpg

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