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肝细胞癌和肝转移瘤热消融术后并发症:影像表现

Complications after Thermal Ablation of Hepatocellular Carcinoma and Liver Metastases: Imaging Findings.

作者信息

De Muzio Federica, Cutolo Carmen, Dell'Aversana Federica, Grassi Francesca, Ravo Ludovica, Ferrante Marilina, Danti Ginevra, Flammia Federica, Simonetti Igino, Palumbo Pierpaolo, Bruno Federico, Pierpaoli Luca, Fusco Roberta, Giovagnoni Andrea, Miele Vittorio, Barile Antonio, Granata Vincenza

机构信息

Department of Medicine and Health Sciences V. Tiberio, University of Molise, 86100 Campobasso, Italy.

Department of Medicine, Surgery and Dentistry, University of Salerno, 84084 Fisciano, Italy.

出版信息

Diagnostics (Basel). 2022 May 5;12(5):1151. doi: 10.3390/diagnostics12051151.

Abstract

Tumour ablation is a strategy of treatment of hepatic tumours in patients with small hepatocellular carcinoma (HCC) (<3 cm) or in patients unfit for surgical resection. Moreover, tumor ablation can be used as an adjuvant therapy or may be used in association with resection in case of patients with poor functional liver disease. These types of treatment usually could be performed percutaneously under image guidance. The most clinically verified and used ablation modalities are Radiofrequency Ablation (RFA) and microwave ablation (MWA). However, despite both of them are considered minimally invasive techniques, they could be related to post-procedural complications. The International Working Group on Image-Guided Tumor and the Society of Interventional Radiology (SIR) identified major and minor post-ablative complications. Major complications, as vascular complications, occur in 2.2% to 3.1% of cases and include all the high risk pathological conditions which could increase the level of care or result in hospital admission or substantially prolonged hospital stay (SIR classifications C−E). Minor complications, as biliary complications, occur in 5% to 8.9% and include self-limiting conditions that are considered to be of low risk for the patient’s outcome. The purpose of this review is to summarise the main pathological ultrasound (US) and Computed Tomography (CT) findings, that may arise after ablative treatment. To simplify the analysis, the pathological pictures are divided according to the site of damage into vascular, biliary and extrahepatic complications.

摘要

肿瘤消融是治疗小肝细胞癌(HCC)(<3 cm)患者或不适于手术切除患者肝脏肿瘤的一种策略。此外,肿瘤消融可作为辅助治疗,或用于肝功能不良患者的联合切除治疗。这些类型的治疗通常可在影像引导下经皮进行。临床上最常用且经证实的消融方式是射频消融(RFA)和微波消融(MWA)。然而,尽管它们都被认为是微创技术,但可能会出现术后并发症。国际影像引导肿瘤工作组和介入放射学会(SIR)确定了消融后主要和次要并发症。主要并发症,如血管并发症,发生率为2.2%至3.1%,包括所有可能增加护理级别、导致住院或显著延长住院时间的高风险病理状况(SIR分类C - E)。次要并发症,如胆道并发症,发生率为5%至8.9%,包括被认为对患者预后风险较低的自限性状况。本综述的目的是总结消融治疗后可能出现的主要病理超声(US)和计算机断层扫描(CT)表现。为简化分析,将病理图像根据损伤部位分为血管、胆道和肝外并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3610/9139664/8e699b949f7c/diagnostics-12-01151-g001.jpg

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