Nephrology Division, Department of Internal Medicine, King Fahad Hospital of the University, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia.
Quality Assurance Department, Deanship of Quality and Academic Accreditation, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia.
Medicina (Kaunas). 2022 May 6;58(5):644. doi: 10.3390/medicina58050644.
Given the current state of COVID-19, it is crucial to reveal its evolving relationship with and effect on different body organ systems and their diseases. The severity and outcome of COVID-19 have a very complex relationship, especially to the vital organs including the kidney, either in their state of health or disease. Additionally, it is well known that diabetes affects the kidney, leading to diabetic nephropathy. The kidney is also affected by different pathological and immunopathological reactions with COVID-19 infection, leading to acute kidney injury. Therefore, this review intended to extract the recent advances, updates, and discoveries about the effects of COVID-19 on diabetic patients and the relationship between COVID-19 invasion and the diabetic kidney and to discuss the current state of knowledge that has not yet been proved or disproved, leading to numerous controversial issues in looking for the effect of COVID-19 associated with diabetes mellitus on the human kidney.
鉴于当前 COVID-19 的情况,揭示其与不同身体器官系统及其疾病的演变关系及其影响至关重要。COVID-19 的严重程度和结果与包括肾脏在内的重要器官之间存在非常复杂的关系,无论是在健康状态还是疾病状态下。此外,众所周知,糖尿病会影响肾脏,导致糖尿病肾病。肾脏也会受到 COVID-19 感染引起的不同病理和免疫病理反应的影响,导致急性肾损伤。因此,本综述旨在提取关于 COVID-19 对糖尿病患者的影响以及 COVID-19 侵袭与糖尿病肾脏之间关系的最新进展、更新和发现,并讨论目前尚未得到证实或反驳的知识现状,导致在寻找 COVID-19 与糖尿病相关对人类肾脏的影响方面存在许多有争议的问题。