一个具有挑战性的诊断：来自骶骨尤因肉瘤病例系列的经验教训。
A challenging diagnosis: Lesson from case series of sacral Ewing sarcoma.
作者信息
Kamal Achmad Fauzi, Cahayadi Sigit Daru, Shihab Reza Abidin, Ramang Didi Saputra
机构信息
Department of Orthopaedic and Traumatology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia.
Department of Orthopaedic and Traumatology, Persahabatan General Hospital, Jakarta, Indonesia.
出版信息
Int J Surg Case Rep. 2022 May;94:107073. doi: 10.1016/j.ijscr.2022.107073. Epub 2022 Apr 12.
BACKGROUND
Ewing's sarcoma is an aggressive bone and the surrounding soft tissue cancer primarily found in children and young adults. It is mostly observed in the trunk and long bones while unusually seen in the sacrum. Sacral Ewing sarcoma has a unique anatomic limitation due to neurological structures, vertebral column, and pelvic involvement. Hence, identifying sacral Ewing's sarcoma remains a challenge.
METHOD
This is a case series including three patients diagnosed with Sacral Ewing's sarcoma. These three cases have been diagnosed based on clinical and radiographic examination, MRI, histopathology, and immunohistochemistry examination.
DISCUSSION
Sacral Ewing's sarcoma remains a challenge to diagnose due to its unique anatomy site. MRI examination is sensitive to detect lesions but nonspecific. Thus, require histopathological confirmation.
CONCLUSION
Early diagnosis of Ewing's sarcoma is essential and we need to perform further examinations, such as immunohistochemistry examination, to confirm the diagnosis of Ewing's sarcoma.
背景
尤因肉瘤是一种侵袭性骨及周围软组织癌症，主要见于儿童和年轻人。它多发生于躯干和长骨，而在骶骨中罕见。由于神经结构、脊柱和骨盆受累，骶骨尤因肉瘤具有独特的解剖学局限性。因此，骶骨尤因肉瘤的诊断仍然是一项挑战。
方法
这是一个病例系列，包括三名被诊断为骶骨尤因肉瘤的患者。这三例均基于临床和影像学检查、磁共振成像（MRI）、组织病理学和免疫组织化学检查确诊。
讨论
由于其独特的解剖部位，骶骨尤因肉瘤的诊断仍然是一项挑战。MRI检查对检测病变敏感但不具特异性。因此，需要组织病理学确认。
结论
尤因肉瘤的早期诊断至关重要，我们需要进行进一步检查，如免疫组织化学检查，以确诊尤因肉瘤。
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