Francinetti Audrey, Vullings Rik, Dewals Wendy, Jochems Lisbeth
Departement of Gynaecology and Obstetrics UZA, Antwerp University Hospital, Drie Eikenstraat 655, 2650 Edegem, Belgium.
Signal Processing Systems group, Eindhoven University of Technology, 5612 AZ Eindhoven, Netherlands.
Eur Heart J Case Rep. 2022 May 24;6(6):ytac213. doi: 10.1093/ehjcr/ytac213. eCollection 2022 Jun.
Maternal tachycardia is the most frequently occurring cardiac complication during pregnancy. Often administration of drugs is required as a treatment. The drug of choice is intravenously administered adenosine because it is considered safe, though there are limited studies regarding safety for the foetus with the use of adenosine.
We report a conversion of maternal atrio-ventricular (AV) nodal reentry tachycardia during pregnancy with the use of intravenous adenosine whilst continuous electrophysiological foetal monitoring. Four seconds after the maternal conversion, the foetal tracing suggests the presence of a ventricular extrasystole or a transient AV block.
This case report illustrates that the administration of adenosine intravenously during pregnancy could have an effect on the foetal conduction system. Therefore, further investigation to assess the electrophysiological effect of adenosine on the foetal electrocardiogram seems required.
孕期母体心动过速是最常见的心脏并发症。通常需要使用药物进行治疗。首选药物是静脉注射腺苷,因为它被认为是安全的,不过关于腺苷对胎儿安全性的研究有限。
我们报告了1例孕期使用静脉注射腺苷转复母体房室结折返性心动过速,同时进行胎儿连续电生理监测的病例。母体转复后4秒,胎儿心电图显示存在室性期前收缩或短暂房室传导阻滞。
本病例报告表明,孕期静脉注射腺苷可能会对胎儿传导系统产生影响。因此,似乎需要进一步研究以评估腺苷对胎儿心电图的电生理效应。