A.E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences, 1 Favorsky Street, 664033 Irkutsk, Russia.
D.V. Sokolskiy Institute of Fuel, Catalysis and Electrochemistry, 142 Kunaev Street, Almaty 050010, Kazakhstan.
Molecules. 2022 May 31;27(11):3549. doi: 10.3390/molecules27113549.
Silatranes arouse much research interest owing to their unique structure, unusual physical-chemical properties, and diverse biological activity. The application of some silatranes and their analogues has been discussed in several works. Meanwhile, a comprehensive review of the wide practical usage of silatranes is still absent in the literature. The ability of silatranes to mildly control hydrolysis allows them to form extremely stable and smooth siloxane monolayers almost on any surface. The high physiological activity of silatranes makes them prospective drug candidates. In the present review, based on the results of numerous previous studies, using the commercially available 3-aminopropylsilatrane and its hybrid derivatives, we have demonstrated the high potential of 1-organylsilatranes in various fields, including chemistry, biology, pharmaceuticals, medicine, agriculture, and industry. For example, these compounds can be employed as plant growth biostimulants, drugs, optical, catalytic, sorption, and special polymeric materials, as well as modern high-tech devices.
硅氮烷由于其独特的结构、不寻常的物理化学性质和多样的生物活性而引起了广泛的研究兴趣。一些硅氮烷及其类似物的应用在几项工作中进行了讨论。同时,硅氮烷的广泛实际用途的综合综述在文献中仍然缺乏。硅氮烷控制水解的温和能力使它们能够在几乎任何表面上形成极其稳定和光滑的硅氧烷单层。硅氮烷的高生理活性使它们成为有前途的药物候选物。在本综述中,根据以往大量研究的结果,使用市售的 3-氨丙基硅氮烷及其杂化衍生物,我们展示了 1-有机硅氮烷在化学、生物学、制药、医学、农业和工业等各个领域的巨大潜力。例如,这些化合物可用作植物生长生物刺激剂、药物、光学、催化、吸附和特殊聚合物材料,以及现代高科技设备。