• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

使用单吻合技术可减少微创直肠手术中的吻合口并发症。

The use of single-stapling techniques reduces anastomotic complications in minimal-invasive rectal surgery.

机构信息

Department of General and Visceral Surgery, Friedrich-Alexander-University, Krankenhausstraße 12, Erlangen, 91054, Germany.

Department of General, Thoracic and Vascular Surgery, Greifswald University, Ferdinand-Sauerbruch-Straße, VisceralGreifswald, Germany.

出版信息

Int J Colorectal Dis. 2022 Jul;37(7):1601-1609. doi: 10.1007/s00384-022-04197-5. Epub 2022 Jun 15.

DOI:10.1007/s00384-022-04197-5
PMID:35704092
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9262801/
Abstract

BACKGROUND

Leakage of rectal anastomoses is one of the most important and feared complications in colorectal surgery. Apart from patient-specific risk factors, technical aspects may influence the occurrence of anastomotic complications. This study investigated whether using single-stapling techniques (SST) instead of the double-stapling technique (DST) for minimal-invasive rectal anastomosis is associated with a lower rate of anastomotic complications.

METHODS

A retrospective review of 272 patients who received a minimally invasive stapled rectal anastomosis (3-16 cm from the anal verge) at our institution from 2015 to 2020 was performed. In 131 patients, rectal anastomosis was created by SST (SST group), while 141 patients received a rectal anastomosis with crossing stapler lines (DST group). The impact of the anastomotic technique on patient outcomes was determined by uni- and multivariate analyses.

RESULTS

Overall anastomotic leakage rate was 6%. Patients with SST anastomoses had a lower leakage rate than patients with DST anastomoses (3% vs. 9% in the DST group, p = 0.045). The rate of anastomotic stenosis was lower in the SST group than in the DST group (1% vs. 6%, p = 0.037). Overall morbidity and mortality did not differ between the two groups. Multivariate analysis showed that single-stapling techniques significantly reduce the risk of anastomotic leakage (OR 3.5 [1.0-11.5], p = 0.043).

CONCLUSION

The use of SST for rectal anastomosis may help to reduce anastomotic complications. This finding should be confirmed by a randomized controlled trial.

摘要

背景

直肠吻合口漏是结直肠外科中最严重和最令人担忧的并发症之一。除了患者特有的危险因素外,技术方面也可能影响吻合口并发症的发生。本研究调查了微创直肠吻合术中使用单吻合技术(SST)代替双吻合技术(DST)是否与较低的吻合口并发症发生率相关。

方法

回顾性分析了 2015 年至 2020 年在我院接受微创吻合直肠吻合术(距肛门缘 3-16cm)的 272 例患者。其中 131 例患者采用 SST 行直肠吻合术(SST 组),141 例患者采用交叉吻合器行直肠吻合术(DST 组)。通过单因素和多因素分析确定吻合技术对患者结局的影响。

结果

总体吻合口漏发生率为 6%。SST 吻合组吻合口漏发生率低于 DST 吻合组(3%比 DST 组的 9%,p=0.045)。SST 组吻合口狭窄发生率低于 DST 组(1%比 DST 组的 6%,p=0.037)。两组间总发病率和死亡率无差异。多因素分析显示,单吻合技术显著降低吻合口漏的风险(OR 3.5[1.0-11.5],p=0.043)。

结论

直肠吻合术中使用 SST 可能有助于降低吻合口并发症。这一发现需要通过随机对照试验来证实。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cfe/9262801/e58b888f9ff5/384_2022_4197_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cfe/9262801/f6688d41e618/384_2022_4197_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cfe/9262801/e58b888f9ff5/384_2022_4197_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cfe/9262801/f6688d41e618/384_2022_4197_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cfe/9262801/e58b888f9ff5/384_2022_4197_Fig2_HTML.jpg

相似文献

1
The use of single-stapling techniques reduces anastomotic complications in minimal-invasive rectal surgery.使用单吻合技术可减少微创直肠手术中的吻合口并发症。
Int J Colorectal Dis. 2022 Jul;37(7):1601-1609. doi: 10.1007/s00384-022-04197-5. Epub 2022 Jun 15.
2
Single-stapled anastomosis is associated with a lower anastomotic leak rate than double-stapled technique after minimally invasive total mesorectal excision for MRI-defined low rectal cancer.在 MRI 定义的低位直肠癌的微创全直肠系膜切除术后,单吻合器吻合与双吻合器技术相比,吻合口漏的发生率更低。
Surgery. 2023 Jun;173(6):1367-1373. doi: 10.1016/j.surg.2023.02.018. Epub 2023 Mar 24.
3
Influence of multiple stapler firings used for rectal division on colorectal anastomotic leak rate.多次使用吻合器切割直肠对结直肠吻合口漏发生率的影响。
Surg Endosc. 2017 Dec;31(12):5318-5326. doi: 10.1007/s00464-017-5611-0. Epub 2017 Jun 20.
4
A novel single-stapling technique for colorectal anastomosis: a pre-ligation single-stapling technique (L-SST) in a porcine model.一种用于结直肠吻合术的新型单吻合器技术:猪模型中的预结扎单吻合器技术(L-SST)
Surg Endosc. 2015 Aug;29(8):2371-6. doi: 10.1007/s00464-014-3960-5. Epub 2014 Dec 6.
5
Preventing complications in colorectal anastomosis: results of a randomized controlled trial using bioabsorbable staple line reinforcement for circular stapler.预防结直肠吻合口并发症:一项使用生物可吸收吻合钉加固圆形吻合器的随机对照试验结果
Dis Colon Rectum. 2014 Oct;57(10):1195-201. doi: 10.1097/DCR.0000000000000207.
6
Outcomes of resection for rectal cancer in India: the impact of the double stapling technique.印度直肠癌切除术的结果:双吻合器技术的影响。
World J Surg Oncol. 2007 Mar 21;5:35. doi: 10.1186/1477-7819-5-35.
7
Fact or fiction? Does the position of the end-to-end (EEA) stapler spike matter for colorectal anastomoses using a double-stapled technique?事实还是虚构?使用双吻合器技术进行结直肠吻合时,端端吻合器(EEA)钉砧的位置是否重要?
Colorectal Dis. 2024 Jan;26(1):137-144. doi: 10.1111/codi.16833. Epub 2023 Dec 11.
8
A new colorectal/coloanal anastomotic technique in sphincter-preserving operation for lower rectal carcinoma using transanal pull-through combined with single stapling technique.经肛门拖出联合单吻合器技术在低位直肠癌保肛手术中的一种新的结直肠/结肠肛管吻合技术。
Int J Colorectal Dis. 2013 Nov;28(11):1517-22. doi: 10.1007/s00384-013-1723-8. Epub 2013 Jun 8.
9
Risk factors for anastomotic leakage after laparoscopic low anterior resection with DST anastomosis.腹腔镜低位前切除联合DST吻合术后吻合口漏的危险因素。
Surg Endosc. 2014 Oct;28(10):2988-95. doi: 10.1007/s00464-014-3564-0. Epub 2014 May 23.
10
Does the Single-Stapling Technique for Circular-Stapled Esophagojejunostomy Reduce Anastomotic Complications After Laparoscopic Total Gastrectomy?腹腔镜全胃切除术后圆形吻合器食管空肠吻合的单吻合器技术能否减少吻合口并发症?
Ann Surg Oncol. 2015 Oct;22(11):3606-12. doi: 10.1245/s10434-015-4417-3. Epub 2015 Feb 7.

引用本文的文献

1
The robotic intracorporeal single-stapled anastomosis (RiSSA) technique in robotic left-sided colorectal resection: a technical note.机器人辅助左侧结直肠癌切除术中的机器人体内单吻合器吻合术(RiSSA)技术:技术说明
Ann Coloproctol. 2025 Aug;41(4):357-360. doi: 10.3393/ac.2025.00486.0069. Epub 2025 Aug 18.
2
Postoperative Morbidity Is Not Associated with a Worse Mid-Term Quality of Life After Colorectal Surgery for Colorectal Carcinoma.结直肠癌手术后的术后发病率与中期生活质量较差无关。
J Clin Med. 2025 Jul 21;14(14):5167. doi: 10.3390/jcm14145167.
3
Stapler for corneal transplantation: a hypothesis.

本文引用的文献

1
Retrospective Risk Analysis for Anastomotic Leakage Following Laparoscopic Rectal Cancer Surgery in a Single Institute.单中心腹腔镜直肠癌术后吻合口漏的回顾性风险分析。
J Gastrointest Cancer. 2020 Sep;51(3):908-913. doi: 10.1007/s12029-019-00315-9.
2
Risk and early predictive factors of anastomotic leakage in laparoscopic low anterior resection for rectal cancer.腹腔镜低位前切除术治疗直肠癌吻合口漏的风险和早期预测因素。
World J Surg Oncol. 2019 Nov 2;17(1):178. doi: 10.1186/s12957-019-1716-3.
3
Surgical-related risk factors associated with anastomotic leakage after resection for rectal cancer: a meta-analysis.
角膜移植吻合器:一种假说。
Med Hypothesis Discov Innov Ophthalmol. 2025 May 10;14(1):239-246. doi: 10.51329/mehdiophthal1515. eCollection 2025 Spring.
4
Laparoscopic Resection and Anastomosis in Bowel Endometriosis: Single Stapler Surgical Technique.肠道子宫内膜异位症的腹腔镜切除与吻合术:单吻合器手术技术
JSLS. 2025 Apr-Jun;29(2). doi: 10.4293/JSLS.2025.00004. Epub 2025 May 6.
5
Circular staplers and anastomotic leakage in colorectal surgery: meta-analysis.圆形吻合器与结直肠手术中的吻合口漏:荟萃分析
BJS Open. 2025 Mar 4;9(2). doi: 10.1093/bjsopen/zrae170.
6
The Effect of Multifaceted Anastomotic Leakage Prevention ICG and SST for Lower Rectal Anastomosis.多层面吻合口漏预防 ICG 和 SST 对低位直肠吻合术的影响。
In Vivo. 2024 Nov-Dec;38(6):2973-2980. doi: 10.21873/invivo.13780.
7
Systemic assessment of manual circular stapler versus powered circular stapler for anastomosis in rectal cancer: a large-scale Chinese multicenter prospective cohort study.直肠癌吻合术中手动圆形吻合器与电动圆形吻合器的系统评估:一项大型中国多中心前瞻性队列研究
Int J Surg. 2025 Jan 1;111(1):1564-1567. doi: 10.1097/JS9.0000000000002010.
8
The Colorectal Anastomosis: A Timeless Challenge.结直肠吻合术:一项永恒的挑战。
Clin Colon Rectal Surg. 2022 Dec 9;36(1):11-28. doi: 10.1055/s-0042-1756510. eCollection 2023 Jan.
直肠癌切除术后吻合口漏的手术相关危险因素:荟萃分析。
Jpn J Clin Oncol. 2020 Jan 24;50(1):20-28. doi: 10.1093/jjco/hyz139.
4
Laparoscopic surgery for rectal cancer reveals comparable oncological outcome even in context of worse short-term results-long-term analysis of nearly 500 patients from two high-volume centers.腹腔镜直肠癌手术即使在短期结果较差的情况下也能获得相似的肿瘤学结果——来自两个大容量中心的近 500 例患者的长期分析。
Int J Colorectal Dis. 2019 Sep;34(9):1541-1550. doi: 10.1007/s00384-019-03350-x. Epub 2019 Jul 15.
5
Laparoscopic Versus Open Resection for Rectal Cancer: A Noninferiority Meta-analysis of Quality of Surgical Resection Outcomes.腹腔镜与开腹直肠癌切除术的比较:手术切除结果质量的非劣效性荟萃分析。
Ann Surg. 2019 May;269(5):849-855. doi: 10.1097/SLA.0000000000003072.
6
Multicenter analysis of risk factors for anastomotic leakage after middle and low rectal cancer resection without diverting stoma: a retrospective study of 319 consecutive patients.无转流造口的中低位直肠癌切除术后吻合口漏危险因素的多中心分析:对319例连续患者的回顾性研究
Int J Colorectal Dis. 2017 Oct;32(10):1431-1437. doi: 10.1007/s00384-017-2875-8. Epub 2017 Aug 2.
7
Diagnosis, treatment, and consequences of anastomotic leakage in colorectal surgery.结直肠手术中吻合口漏的诊断、治疗及后果
Int J Colorectal Dis. 2017 Apr;32(4):549-556. doi: 10.1007/s00384-016-2744-x. Epub 2017 Jan 9.
8
Natural Orifice Specimen Extraction With Single Stapling Colorectal Anastomosis for Laparoscopic Anterior Resection: Feasibility, Outcomes, and Technical Considerations.经自然腔道标本取出术联合单吻合器技术行腹腔镜直肠癌前切除术:可行性、疗效及技术要点
Dis Colon Rectum. 2017 Jan;60(1):43-50. doi: 10.1097/DCR.0000000000000739.
9
Impact of Preoperative Radiotherapy on Anastomotic Leakage and Stenosis After Rectal Cancer Resection: Post Hoc Analysis of a Randomized Controlled Trial.术前放疗对直肠癌切除术后吻合口漏和狭窄的影响:一项随机对照试验的事后分析
Dis Colon Rectum. 2016 Oct;59(10):934-42. doi: 10.1097/DCR.0000000000000665.
10
The burden of gastrointestinal anastomotic leaks: an evaluation of clinical and economic outcomes.胃肠道吻合口漏的负担:临床和经济结局的评估。
J Gastrointest Surg. 2014 Jun;18(6):1176-85. doi: 10.1007/s11605-014-2506-4.