Institut Necker Enfants Malades, Institut National de la Santé et de la Recherche Médicale (INSERM) U 1151, Centre National de la Recherche Scientifique (CNRS) UMR 8253, Paris, France.
Institut Necker Enfants Malades, Institut National de la Santé et de la Recherche Médicale (INSERM) U 1151, Centre National de la Recherche Scientifique (CNRS) UMR 8253, Paris, France; Université Paris Cité, Faculté de Médecine, Paris, France; AP-HP, Hôpital Necker-Enfants Malades, Paris, France.
Immunity. 2022 Jun 14;55(6):970-972. doi: 10.1016/j.immuni.2022.05.011.
Regulatory B cells infiltrate the microenvironment of solid tumors. However, their identification and characterization remain incomplete. In this issue of Immunity, Wang and colleagues characterize a new subset of leucine-induced regulatory B cells involved in colorectal cancer (CRC) immunoevasion in mice and humans.
调节性 B 细胞浸润实体肿瘤的微环境。然而,它们的鉴定和特征仍不完全。在本期《免疫》中,Wang 及其同事描述了一种新的亮氨酸诱导的调节性 B 细胞亚群,该亚群参与了小鼠和人类结直肠癌(CRC)的免疫逃逸。