Student Research Committee, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
Student Research Committee, Department of Pediatric Dentistry, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
J Mater Sci Mater Med. 2022 Jun 18;33(7):55. doi: 10.1007/s10856-022-06676-1.
Stem cells exist as normal cells in embryonic and adult tissues. In recent years, scientists have spared efforts to determine the role of stem cells in treating many diseases. Stem cells can self-regenerate and transform into some somatic cells. They would also have a special position in the future in various clinical fields, drug discovery, and other scientific research. Accordingly, the detection of safe and low-cost methods to obtain such cells is one of the main objectives of research. Jaw, face, and mouth tissues are the rich sources of stem cells, which more accessible than other stem cells, so stem cell and tissue engineering treatments in dentistry have received much clinical attention in recent years. This review study examines three essential elements of tissue engineering in dentistry and clinical practice, including stem cells derived from the intra- and extra-oral sources, growth factors, and scaffolds.
干细胞作为正常细胞存在于胚胎和成人组织中。近年来,科学家们不遗余力地确定干细胞在治疗许多疾病中的作用。干细胞可以自我更新并转化为某些体细胞。它们在未来的各个临床领域、药物发现和其他科学研究中也将具有特殊地位。因此,寻找安全且低成本的方法来获得此类细胞是研究的主要目标之一。颌面部和口腔组织是干细胞的丰富来源,它们比其他干细胞更容易获得,因此近年来,口腔干细胞和组织工程治疗在牙科领域受到了广泛关注。本综述研究检查了牙科临床实践中组织工程的三个基本要素,包括来自口腔内外源的干细胞、生长因子和支架。