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小脑阳极经颅直流电刺激是否适合多发性硬化症患者的运动干预?

Is cerebellar anodal transcranial direct current stimulation an appropriate locomotor intervention for people with multiple sclerosis?

机构信息

Department of Health and Exercise Science, Colorado State University, Fort Collins, Colorado.

出版信息

J Neurophysiol. 2022 Jul 1;128(1):250-252. doi: 10.1152/jn.00156.2022. Epub 2022 Jun 22.

Abstract

The present article demonstrates split-belt treadmill training, but not cerebellar transcranial direct current stimulation (tDCS), reduces fall risk for people with multiple sclerosis. Concerns regarding the implementation of the split-belt paradigm, coupled with insensitive outcome measures and a nonoptimal neural target for tDCS may have contributed to the limited gait improvements observed. A more fitting stimulation may be to target nervous system structures in the periphery to improve sensorimotor transduction and elicit more accurate proprioception.

摘要

本文表明,分带跑步机训练而非小脑经颅直流电刺激(tDCS)可降低多发性硬化症患者的跌倒风险。对分带范式实施的担忧,加上不敏感的结果测量和 tDCS 的非最佳神经靶点,可能导致观察到的步态改善有限。更合适的刺激可能是针对外周神经系统结构,以改善感觉运动转导并引出更准确的本体感觉。

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