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[小儿肾脓肿:一项诊断挑战]

[Pediatric renal abscesses: a diagnostic challenge].

作者信息

Jiménez Martha, Gajardo Macarena, Bolte Lillian, Lazcano Andrea, Salgado Ignacio

机构信息

Facultad de Medicina, Universidad de Chile, Santiago, Chile.

Hospital Roberto del Río, Santiago, Chile.

出版信息

Andes Pediatr. 2022 Apr;93(2):222-228. doi: 10.32641/andespediatr.v93i2.3765.

Abstract

UNLABELLED

Kidney abscess is an unusual entity in childhood with few studies about its clinical characteris tics.

OBJECTIVE

To report the clinical presentation, diagnosis, and therapy used in a cohort of 20 children with kidney abscess.

PATIENTS AND METHOD

retrospective study of cases of kidney abscess during a 10-year period at the Hospital Roberto del Río. The analysis of clinical, laboratory, and imaging characteristics were evaluated as well as the treatment usedfor this condition.

RESULTS

20 cases were reported among which 65% were women with a median age of 3.6 years. The most com mon clinical presentation was fever, vomit, and dysuria. Eighty percent of patients presented an increase of inflammatory parameters, 88% presented positive urine culture, and the most common organism identified was Escherichia Coli (77.8%). The diagnosis was mostly made through kidney ultrasound (75%) followed by an abdominal CT scan (35%). 93% of abscesses were unilateral. About 95% of the patients only required antibiotic treatment. Vesicoureteral reflux was diagno sed in 28% of the patients with no sphincter control, and only one of them presented high-grade reflux. In patients with sphincter control, bladder and bowel dysfunction (BBD) was diagnosed in 90% of the cases. Forty four percent of the patients with late DMSA renal scintigraphy presented renal scarring.

CONCLUSIONS

In this series, pediatric kidney abscess appears with persistent fever despite the treatment, requiring prolonged antibiotic therapy and rarely surgical drains. We su ggest a study aimed at detecting modifiable factors, such as vesicoureteral reflux in patients with no sphincter control and BBD in patients with sphincter control, as well as identifying renal paren chymal sequels in all patients.

摘要

未标注

肾脓肿在儿童中是一种不常见的疾病,关于其临床特征的研究较少。

目的

报告20例儿童肾脓肿患者的临床表现、诊断和治疗情况。

患者与方法

对罗伯托·德尔·里奥医院10年间肾脓肿病例进行回顾性研究。评估临床、实验室和影像学特征以及针对该疾病的治疗方法。

结果

报告了20例病例,其中65%为女性,中位年龄为3.6岁。最常见的临床表现是发热、呕吐和排尿困难。80%的患者炎症参数升高,88%的患者尿培养呈阳性,最常见的病原体是大肠杆菌(77.8%)。诊断主要通过肾脏超声(75%),其次是腹部CT扫描(35%)。93%的脓肿为单侧。约95%的患者仅需抗生素治疗。在无括约肌控制的患者中,28%诊断出膀胱输尿管反流,其中只有1例为重度反流。在有括约肌控制的患者中,90%的病例诊断出膀胱和肠道功能障碍(BBD)。延迟DMSA肾闪烁显像的患者中,44%出现肾瘢痕形成。

结论

在本系列研究中,儿童肾脓肿在治疗后仍表现为持续发热,需要长期抗生素治疗,很少需要手术引流。我们建议开展一项研究,旨在检测可改变的因素,如无括约肌控制患者的膀胱输尿管反流和有括约肌控制患者的BBD,以及识别所有患者的肾实质后遗症。

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