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O18脂多糖的磷酸胆碱修饰可诱导细胞表面的疏水性和动电电位,但不会改变对固体表面的粘附性。

Phosphocholine decoration of O18 LPS induces hydrophobicity of the cell surface and electrokinetic potential, but does not alter the adhesion to solid surfaces.

作者信息

Czerwonka Grzegorz, Durlik-Popińska Katarzyna, Drabik Marcin, Szczerba Martyna, Kwiatkowska Maria, Kaca Wiesław

机构信息

Department of Microbiology, Institute of Biology, Jan Kochanowski University, Kielce, Poland.

Department of Astrophysics, Institute of Physics, Jan Kochanowski University, Kielce, Poland.

出版信息

Cell Surf. 2022 Jun 15;8:100079. doi: 10.1016/j.tcsw.2022.100079. eCollection 2022 Dec.

Abstract

harbours a variety of O antigens, permitting evasion of the host immune response. LPS decoration with phosphocholine increases cell surface hydrophobicity and decreases electrokinetic potential, which may interfere with antibody interaction and bacterial surface recognition. The decoration does not influence adherence to solid surfaces.

摘要

携带多种O抗原,从而逃避免疫反应。用磷酸胆碱修饰脂多糖会增加细胞表面疏水性并降低动电电位,这可能会干扰抗体相互作用和细菌表面识别。这种修饰不会影响对固体表面的黏附。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b8d/9213243/88b762079ff1/gr1.jpg

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