Pallares-Carratala Vicente, Carratala-Munuera Concepcion, Lopez-Pineda Adriana, Quesada Jose Antonio, Gil-Guillen Vicente, Orozco-Beltran Domingo, Alfonso-Sanchez Jose L, Navarro-Perez Jorge, Martin-Moreno Jose M
Health Surveillance Unit, Castellon Mutual Insurance Union, Castellón, Spain.
Department of Medicine, Jaume I University, Castellón, Spain.
Front Cardiovasc Med. 2022 Jun 16;9:874764. doi: 10.3389/fcvm.2022.874764. eCollection 2022.
Substantial evidence shows that diagnostic inertia leads to failure to achieve screening and diagnosis objectives for arterial hypertension (AHT). In addition, different studies suggest that the results may differ between men and women. This study aimed to evaluate the differences in diagnostic inertia in women and men attending public primary care centers, to identify potential gender biases in the clinical management of AHT.
STUDY DESIGN/MATERIALS AND METHODS: Cross-sectional descriptive and analytical estimates were obtained nested on an epidemiological ambispective cohort study of patients aged ≥30 years who attended public primary care centers in a Spanish region in the period 2008-2012, belonging to the ESCARVAL-RISK cohort. We applied a consistent operational definition of diagnostic inertia to a registry- reflected population group of 44,221 patients with diagnosed hypertension or meeting the criteria for diagnosis (51.2% women), with a mean age of 63.4 years (62.4 years in men and 64.4 years in women).
Of the total population, 95.5% had a diagnosis of hypertension registered in their electronic health record. Another 1,968 patients met the inclusion criteria for diagnostic inertia of hypertension, representing 4.5% of the total population (5% of men and 3.9% of women). The factors significantly associated with inertia were younger age, normal body mass index, elevated total cholesterol, coexistence of diabetes and dyslipidemia, and treatment with oral antidiabetic drugs. Lower inertia was associated with age over 50 years, higher body mass index, normal total cholesterol, no diabetes or dyslipidemia, and treatment with lipid-lowering, antiplatelet, and anticoagulant drugs. The only gender difference in the association of factors with diagnostic inertia was found in waist circumference.
In the ESCARVAL-RISK study population presenting registered AHT or meeting the functional diagnostic criteria for AHT, diagnostic inertia appears to be greater in men than in women.
大量证据表明,诊断惰性会导致未能实现动脉高血压(AHT)的筛查和诊断目标。此外,不同研究表明,男性和女性的结果可能存在差异。本研究旨在评估在公立基层医疗中心就诊的男性和女性在诊断惰性方面的差异,以确定AHT临床管理中潜在的性别偏见。
研究设计/材料与方法:在一项针对2008 - 2012年期间在西班牙某地区公立基层医疗中心就诊的≥30岁患者的流行病学双向队列研究中,获得横断面描述性和分析性估计值,这些患者属于ESCARVAL - RISK队列。我们将诊断惰性的一致操作定义应用于一个由44,221名已确诊高血压或符合诊断标准的患者组成的登记反映人群组(女性占51.2%),平均年龄为63.4岁(男性为62.4岁,女性为64.4岁)。
在总人口中,95.5%的人在其电子健康记录中有高血压诊断。另外1968名患者符合高血压诊断惰性的纳入标准,占总人口的4.5%(男性为5%,女性为3.9%)。与惰性显著相关的因素包括年龄较小、体重指数正常、总胆固醇升高、糖尿病和血脂异常并存以及口服抗糖尿病药物治疗。较低的惰性与50岁以上年龄、较高的体重指数、总胆固醇正常、无糖尿病或血脂异常以及使用降脂、抗血小板和抗凝药物治疗有关。在与诊断惰性相关的因素关联中,唯一的性别差异在于腰围。
在ESCARVAL - RISK研究人群中,那些已登记患有AHT或符合AHT功能诊断标准的患者中,男性的诊断惰性似乎比女性更大。