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静态与可扩张椎间融合器:微创经椎间孔腰椎椎间融合术1年临床和影像学结果比较

Static versus Expandable Interbody Fusion Devices: A Comparison of 1-Year Clinical and Radiographic Outcomes in Minimally Invasive Transforaminal Lumbar Interbody Fusion.

作者信息

Ledesma Jonathan Andrew, Lambrechts Mark J, Dees Azra, Thomas Terence, Hiranaka Cannon Greco, Kurd Mark Faisal, Radcliff Kris E, Anderson David Greg

机构信息

Rothman Orthopaedic Institute, Thomas Jefferson University, Philadelphia, PA, USA.

出版信息

Asian Spine J. 2023 Feb;17(1):61-74. doi: 10.31616/asj.2021.0486. Epub 2022 Jul 4.

Abstract

STUDY DESIGN

Retrospective cohort study.

PURPOSE

To compare the radiographic and clinical outcomes of static versus expandable interbody cages in transforaminal lumbar interbody fusion using minimally invasive surgery (MIS-TLIF).

OVERVIEW OF LITERATURE

Expandable interbody cages may potentially improve radiographic and clinical outcomes following MIS-TLIF compared to static pages, but at a potentially higher cost and increased rates of subsidence.

METHODS

A retrospective chart review of 1- and 2-level MIS-TLIFs performed from 2014 to 2020 was reviewed. Radiographic measurements were obtained preoperatively, 6 weeks postoperatively, and at final follow-up. Patient-reported outcome measures (PROMs) including the Oswestry Disability Index, Visual Analog Scale (VAS) back, and VAS leg were evaluated. Multivariate linear regression analysis determined the effect of cage type on the change in PROMs, controlling for demographic characteristics. Alpha was set at 0.05.

RESULTS

A total of 221 patients underwent MIS-TLIF including 136 static and 85 expandable cages. Expandable cages had significantly greater anterior (static: 11.41 mm vs. expandable: 13.11 mm, p <0.001) and posterior disk heights (static: 7.22 mm vs. expandable: 8.11 mm, p <0.001) at 1-year follow-up. Expandable cages offered similar improvements in segmental lordosis at 6 weeks (static: 1.69° vs. expandable: 2.81°, p =0.243), but segmental lordosis was better maintained with expandable cages leading to significant differences at 1-year follow-up (static: 0.86° vs. expandable: 2.45°, p =0.001). No significant differences were noted in total complication (static: 12.5% vs. expandable: 16.5%, p =0.191) or cage subsidence rates (static: 19.7% vs. expandable: 22.4%, p =0.502) groups at 1-year follow-up.

CONCLUSIONS

Expandable devices provide greater improvements in radiographic measurements including anterior disk height, posterior disk height, and segmental lordosis, but this did not lead to significant improvements in PROMs, complication rates, subsidence rates, or subsidence distance.

摘要

研究设计

回顾性队列研究。

目的

比较在微创经椎间孔腰椎椎间融合术(MIS-TLIF)中使用静态与可扩张椎间融合器的影像学和临床结果。

文献综述

与静态椎间融合器相比,可扩张椎间融合器可能会改善MIS-TLIF术后的影像学和临床结果,但成本可能更高且下沉率增加。

方法

对2014年至2020年进行的1级和2级MIS-TLIF手术进行回顾性病历审查。在术前、术后6周和最终随访时进行影像学测量。评估患者报告的结局指标(PROMs),包括Oswestry功能障碍指数、视觉模拟量表(VAS)背痛评分和VAS腿痛评分。多变量线性回归分析确定椎间融合器类型对PROMs变化的影响,并对人口统计学特征进行控制。α设定为0.05。

结果

共有221例患者接受了MIS-TLIF手术,其中136例使用静态椎间融合器,85例使用可扩张椎间融合器。在1年随访时,可扩张椎间融合器的前间隙高度(静态:11.41mm vs. 可扩张:13.11mm,p<0.001)和后间隙高度(静态:7.22mm vs. 可扩张:8.11mm,p<0.001)显著更高。可扩张椎间融合器在术后6周时节段前凸改善情况相似(静态:1.69° vs. 可扩张:2.81°,p=0.243),但可扩张椎间融合器能更好地维持节段前凸,在1年随访时导致显著差异(静态:0.86° vs. 可扩张:2.45°,p=0.001)。在1年随访时,两组的总并发症发生率(静态:12.5% vs. 可扩张:16.5%,p=0.191)或椎间融合器下沉率(静态:19.7% vs. 可扩张:22.4%,p=0.502)无显著差异。

结论

可扩张装置在包括前间隙高度、后间隙高度和节段前凸等影像学测量方面有更大改善,但这并未导致PROMs、并发症发生率、下沉率或下沉距离有显著改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/09b7/9977975/61cb2bf6585b/asj-2021-0486f1.jpg

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