Department of Orthopaedic Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Department of Orthopaedic Surgery, JA Hiroshima General Hospital, Hiroshima, Japan.
World Neurosurg. 2022 Sep;165:e712-e720. doi: 10.1016/j.wneu.2022.06.125. Epub 2022 Jul 3.
Percutaneous intervertebral-vacuum polymethylmethacrylate injection (PIPI) is a minimally invasive procedure for low back pain in elderly patients with degenerative lumbar scoliosis (DLS). Patients with DLS often have radiculopathy as a result of foraminal stenosis in addition to low back pain. The purpose of this study was to evaluate the clinical and radiologic results of PIPI for foraminal stenosis with radiculopathy in elderly patients with DLS.
We included patients with de novo DLS aged 65 years or older who underwent PIPI. The presence of an intervertebral vacuum on computed tomography and bone marrow edema on magnetic resonance imaging was required for inclusion. The intersegmental radiologic parameters on plain radiographs and computed tomography and the extent of bone marrow edema on magnetic resonance imaging were measured. The clinical outcomes were evaluated using the visual analog scale (VAS) and Oswestry Disability Index (ODI).
We enrolled 40 patients with DLS who underwent PIPI. There were 16 men and 24 women, and the mean age was 79.0 ± 6.3 years. The mean foraminal height and extent of bone marrow edema showed a significant increase and reduction, respectively, after PIPI (P < 0.05). VAS score for radiculopathy and ODI significantly improved after PIPI (P < 0.01). The minimum clinically important differences in VAS score for radiculopathy and ODI at the final follow-up were 73.9% and 63.6%, respectively.
PIPI is a minimally invasive procedure not only for low back pain but also for radiculopathy in elderly patients with DLS. It leads to intervertebral stabilization and indirect decompression of the foramen.
经皮椎间真空聚甲基丙烯酸甲酯注射(PIPI)是一种治疗老年退行性腰椎侧凸(DLS)伴根性痛患者腰痛的微创方法。DLS 患者除腰痛外,常因椎间孔狭窄而出现根性病变。本研究旨在评估 PIPI 治疗老年退行性腰椎侧凸伴根性痛患者椎间孔狭窄的临床和影像学结果。
我们纳入了年龄在 65 岁及以上且接受 PIPI 治疗的新发 DLS 患者。纳入标准为 CT 显示椎间隙真空征,MRI 显示骨髓水肿。在 X 线和平扫 CT 上测量节段性放射学参数,在 MRI 上测量骨髓水肿程度。采用视觉模拟评分(VAS)和 Oswestry 功能障碍指数(ODI)评估临床结果。
我们纳入了 40 例接受 PIPI 治疗的 DLS 患者,其中男性 16 例,女性 24 例,平均年龄为 79.0±6.3 岁。PIPI 后椎间孔高度和骨髓水肿程度均显著增加和减少(P<0.05)。PIPI 后根性痛 VAS 评分和 ODI 显著改善(P<0.01)。末次随访时,根性痛 VAS 评分和 ODI 的最小临床重要差异分别为 73.9%和 63.6%。
PIPI 不仅是一种治疗老年退行性腰椎侧凸患者腰痛的微创方法,也是一种治疗老年退行性腰椎侧凸患者根性痛的方法。它可导致椎间稳定和间接椎间孔减压。