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夸祖鲁-纳塔尔省地区医院的急性心肌梗死——治疗和预后。

Acute myocardial infarction at a district hospital in KwaZulu-Natal - Management and outcomes.

机构信息

Department of Family Medicine, College of Health Sciences, University of KwaZulu-Natal, Durban.

出版信息

S Afr Fam Pract (2004). 2022 Jun 13;64(1):e1-e8. doi: 10.4102/safp.v64i1.5463.

Abstract

BACKGROUND

Acute myocardial infarction (AMI) following ischaemic heart disease (IHD) is associated with increased morbidity and mortality. The condition remains a management challenge in resource-constrained environments. This study analysed the management and outcomes of patients presenting with AMI at a district hospital in KwaZulu-Natal.

METHODS

A descriptive study that assessed hospital records of all patients diagnosed with AMI over a 2-year period (01 August 2016 to 31 July 2018). Data extracted recorded patient demographics, risk factors, timing of care, therapeutic interventions, follow up with cardiology and mortality of patients.

RESULTS

Of the 140 patients who were admitted with AMI, 96 hospital records were analysed. The mean (standard deviation [s.d.]) age of patients was 55.8 (±12.7) years. Smoking (73.5%) and hypertension (63.3%) were the most prevalent risk factors for patients with ST elevation myocardial infarction (STEMI) in contrast to dyslipidaemia (70.2%) and hypertension (68.1%) in patients with non-ST elevation myocardial infarction (NSTEMI). Almost 49.5% of patients arrived at hospital more than 6 h after symptom onset. Three (12.5%) patients received thrombolytic therapy within the recommended 30-min time frame. The mean triage-to-needle time was 183 min - range (3; 550). Median time to cardiology appointment was 93 days. The in-hospital mortality of 12 deaths considering 140 admissions was 8.6%.

CONCLUSION

In a resource-constrained environment with multiple systemic challenges, in-hospital mortality is comparable to that in private sector conditions in South Africa. This entrenches the role of the family physician. There is need for more coordinated systems of care for AMI between district hospitals and tertiary referral centres.

摘要

背景

缺血性心脏病(IHD)引起的急性心肌梗死(AMI)与发病率和死亡率的增加有关。在资源有限的环境中,这种情况仍然是一个管理挑战。本研究分析了夸祖鲁-纳塔尔省一家地区医院收治的 AMI 患者的治疗方法和结果。

方法

这是一项描述性研究,评估了在两年期间(2016 年 8 月 1 日至 2018 年 7 月 31 日)被诊断为 AMI 的所有患者的医院记录。提取的数据记录了患者的人口统计学、风险因素、护理时间、治疗干预、与心脏病学的随访和患者的死亡率。

结果

在 140 名因 AMI 住院的患者中,分析了 96 份病历。患者的平均(标准差[SD])年龄为 55.8(±12.7)岁。吸烟(73.5%)和高血压(63.3%)是 ST 段抬高型心肌梗死(STEMI)患者最常见的风险因素,而血脂异常(70.2%)和高血压(68.1%)是非 ST 段抬高型心肌梗死(NSTEMI)患者最常见的风险因素。几乎有 49.5%的患者在症状发作后 6 小时以上到达医院。3(12.5%)名患者在推荐的 30 分钟内接受了溶栓治疗。从分诊到针刺的平均时间为 183 分钟-范围(3;550)。中位数到达心脏病学预约的时间为 93 天。考虑到 140 例入院,12 例死亡的院内死亡率为 8.6%。

结论

在资源有限且存在多种系统性挑战的环境中,院内死亡率与南非私营部门的条件相当。这巩固了家庭医生的作用。需要在地区医院和三级转诊中心之间建立更协调的 AMI 护理系统。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85cd/9257761/a504877aa600/SAFP-64-5463-g001.jpg

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