School of Health and Consumer Sciences, South Dakota State University, Brookings, SD 57007, USA.
Department of Health, Human Performance, and Recreation, Baylor University, Waco, TX 76798, USA.
Nutrients. 2022 Jun 29;14(13):2717. doi: 10.3390/nu14132717.
There is conflicting evidence of the roles vitamin D and iron have in isolation and combined in relation to muscle health. The purpose of this narrative review was to examine the current literature on the roles that vitamin D and iron have on skeletal muscle mass, strength, and function and how these nutrients are associated with skeletal muscle health in specific populations. Secondary purposes include exploring if low vitamin D and iron status are interrelated with skeletal muscle health and chronic inflammation and reviewing the influence of animal-source foods rich in these nutrients on health and performance. PubMed, Scopus, SPORT Discus, EMBAE, MEDLINE, and Google Scholar databases were searched to determine eligible studies. There was a positive effect of vitamin D on muscle mass, particularly in older adults. There was a positive effect of iron on aerobic and anaerobic performance. Studies reported mixed results for both vitamin D and iron on muscle strength and function. While vitamin D and iron deficiency commonly occur in combination, few studies examined effects on skeletal muscle health and inflammation. Isolated nutrients such as iron and vitamin D may have positive outcomes; however, nutrients within food sources may be most effective in improving skeletal muscle health.
关于维生素 D 和铁在孤立和联合状态下与肌肉健康的关系，目前存在相互矛盾的证据。本综述的目的是研究目前关于维生素 D 和铁在骨骼肌质量、力量和功能中的作用的文献，以及这些营养素如何与特定人群的骨骼肌健康相关。次要目的包括探索低维生素 D 和铁状态是否与骨骼肌健康和慢性炎症相关，并回顾富含这些营养素的动物源性食物对健康和表现的影响。检索了 PubMed、Scopus、SPORT Discus、EMBASE、MEDLINE 和 Google Scholar 数据库，以确定符合条件的研究。维生素 D 对肌肉质量有积极影响，尤其是在老年人中。铁对有氧运动和无氧运动表现有积极影响。关于维生素 D 和铁对肌肉力量和功能的影响，研究结果不一。虽然维生素 D 和铁缺乏通常同时发生，但很少有研究检查它们对骨骼肌健康和炎症的影响。单独的营养素，如铁和维生素 D，可能有积极的结果；然而，食物来源中的营养素可能最有效地改善骨骼肌健康。
